Detailed information NTG0349319

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: EYB46_RS13085
• Genome accession: NZ_CP036518
• Coordinates: 2665153..2666316 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain ANSB01E
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2660153..2671316

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EYB46_RS13065 (EYB46_13060)	-	2660593..2661789 (+)	1197	WP_032876154.1	glycosyltransferase	-
EYB46_RS13070 (EYB46_13065)	-	2661922..2662998 (+)	1077	WP_003151382.1	MraY family glycosyltransferase	-
EYB46_RS13075 (EYB46_13070)	-	2663097..2664278 (-)	1182	WP_032876157.1	LCP family protein	-
EYB46_RS13080 (EYB46_13075)	-	2664283..2664930 (-)	648	WP_007614107.1	YigZ family protein	-
EYB46_RS13085 (EYB46_13080)	degS	2665153..2666316 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
EYB46_RS13090 (EYB46_13085)	degU	2666393..2667082 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
EYB46_RS13095 (EYB46_13090)	-	2667180..2668028 (+)	849	WP_032876160.1	DegV family protein	-
EYB46_RS13100 (EYB46_13095)	-	2668137..2669521 (+)	1385	Protein_2517	DEAD/DEAH box helicase	-
EYB46_RS13105 (EYB46_13100)	-	2669579..2669863 (+)	285	WP_003151389.1	competence protein ComFB	-
EYB46_RS13110 (EYB46_13105)	comFC	2669869..2670558 (+)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
EYB46_RS13115 (EYB46_13110)	-	2670632..2671051 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=349319 EYB46_RS13085 WP_007407484.1 2665153..2666316(+) (degS) [Bacillus velezensis strain ANSB01E]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=349319 EYB46_RS13085 WP_007407484.1 2665153..2666316(+) (degS) [Bacillus velezensis strain ANSB01E]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951