Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   EXW38_RS13765 Genome accession   NZ_CP036026
Coordinates   2659513..2660094 (-) Length   193 a.a.
NCBI ID   WP_002161520.1    Uniprot ID   J8EDT0
Organism   Bacillus mycoides strain BPN54/2     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 2654513..2665094
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXW38_RS13735 (EXW38_13915) - 2655106..2655606 (-) 501 WP_080025076.1 HIT family protein -
  EXW38_RS13740 (EXW38_13920) - 2655732..2655905 (-) 174 WP_002161523.1 hypothetical protein -
  EXW38_RS13745 (EXW38_13925) - 2656120..2656356 (+) 237 WP_078182070.1 hypothetical protein -
  EXW38_RS13750 (EXW38_13930) - 2656404..2657240 (-) 837 WP_078182071.1 ABC transporter permease -
  EXW38_RS13755 (EXW38_13935) - 2657233..2658438 (-) 1206 WP_000370622.1 quaternary amine ABC transporter ATP-binding protein -
  EXW38_RS13760 (EXW38_13940) - 2658610..2659467 (+) 858 WP_088078694.1 glycine betaine ABC transporter substrate-binding protein -
  EXW38_RS13765 (EXW38_13945) clpP 2659513..2660094 (-) 582 WP_002161520.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  EXW38_RS13770 (EXW38_13950) - 2660115..2660801 (-) 687 WP_088078695.1 RNA polymerase subunit sigma-70 -
  EXW38_RS13775 (EXW38_13955) - 2660945..2661265 (+) 321 WP_078182072.1 2Fe-2S iron-sulfur cluster-binding protein -
  EXW38_RS13780 (EXW38_13960) rpiA 2661270..2661932 (+) 663 WP_088078696.1 ribose 5-phosphate isomerase A -
  EXW38_RS13785 (EXW38_13965) - 2662045..2662479 (+) 435 WP_016105069.1 GNAT family N-acetyltransferase -
  EXW38_RS13790 (EXW38_13970) - 2662623..2663816 (-) 1194 WP_215571713.1 macrolide family glycosyltransferase -
  EXW38_RS13795 (EXW38_13975) - 2663909..2664553 (-) 645 WP_165497471.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21250.53 Da        Isoelectric Point: 5.0906

>NTDB_id=346032 EXW38_RS13765 WP_002161520.1 2659513..2660094(-) (clpP) [Bacillus mycoides strain BPN54/2]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIIMIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLAGAKGKRFALPNSEIMIHQPLGGVKGQATEIEITAKRILKLKHDINKIISDRTGQ
PVEKVAHDTERDYFMTAEEAKEYGIVDDVVTKK

Nucleotide


Download         Length: 582 bp        

>NTDB_id=346032 EXW38_RS13765 WP_002161520.1 2659513..2660094(-) (clpP) [Bacillus mycoides strain BPN54/2]
ATGAATGCAATTCCTTACGTAGTAGAACAAACGAAATTAGGAGAACGCTCCTATGATATATATTCAAGATTATTAAAGGA
CCGAATTATTATGATTGGTTCAGAAATTAACGATCAAGTTGCAAGCAGTGTAGTAGCACAATTATTATTTTTAGAAGCGG
AAGACGCAGAAAAAGATATATTCCTCTATATCAATAGTCCGGGCGGTTCAACGACAGCGGGATTTGCAATATTAGATACG
ATGAACCTTATTAAACCAGATGTGCAAACACTTTGTATGGGCTTTGCGGCATCATTTGGTGCGCTTTTACTATTAGCTGG
CGCAAAGGGAAAAAGATTTGCGCTCCCTAACAGTGAAATCATGATTCATCAACCGCTCGGCGGTGTAAAAGGGCAAGCGA
CGGAGATTGAGATTACAGCAAAAAGAATATTAAAGTTAAAACATGATATTAACAAAATCATATCTGATCGAACAGGGCAA
CCAGTAGAAAAGGTAGCTCATGATACAGAAAGAGATTATTTTATGACTGCAGAAGAAGCGAAGGAATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J8EDT0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.586

98.964

0.679
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.783

97.927

0.674
  clpP Streptococcus thermophilus LMG 18311

56.25

99.482

0.56
  clpP Streptococcus thermophilus LMD-9

56.25

99.482

0.56
  clpP Streptococcus pneumoniae Rx1

55.729

99.482

0.554
  clpP Streptococcus pneumoniae D39

55.729

99.482

0.554
  clpP Streptococcus pneumoniae R6

55.729

99.482

0.554
  clpP Streptococcus pneumoniae TIGR4

55.729

99.482

0.554
  clpP Streptococcus mutans UA159

55.026

97.927

0.539
  clpP Streptococcus pyogenes JRS4

55.026

97.927

0.539
  clpP Streptococcus pyogenes MGAS315

55.026

97.927

0.539
  clpP Lactococcus lactis subsp. cremoris KW2

52.381

97.927

0.513
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

51.323

97.927

0.503

Multiple sequence alignment