Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   ETT46_RS08130 Genome accession   NZ_CP035453
Coordinates   1562400..1562951 (-) Length   183 a.a.
NCBI ID   WP_136265115.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm100     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1557400..1567951
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT46_RS08105 (ETT46_08100) - 1558766..1559611 (+) 846 WP_002982833.1 mechanosensitive ion channel family protein -
  ETT46_RS08110 (ETT46_08105) - 1559676..1560236 (-) 561 WP_002995157.1 TIGR01440 family protein -
  ETT46_RS08115 (ETT46_08110) - 1560250..1560720 (-) 471 WP_020905474.1 ECF transporter S component -
  ETT46_RS08120 (ETT46_08115) - 1560710..1561474 (-) 765 WP_002982821.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  ETT46_RS08125 (ETT46_08120) truA 1561464..1562213 (-) 750 WP_002995162.1 tRNA pseudouridine(38-40) synthase TruA -
  ETT46_RS08130 (ETT46_08125) comX/sigX/comX2/sigX2 1562400..1562951 (-) 552 WP_136265115.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22255.05 Da        Isoelectric Point: 10.0828

>NTDB_id=342425 ETT46_RS08130 WP_136265115.1 1562400..1562951(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm100]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
HRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=342425 ETT46_RS08130 WP_136265115.1 1562400..1562951(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm100]
ATGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
CATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

81.967

0.399
  comX Streptococcus sobrinus strain NIDR 6715-7

46.104

84.153

0.388
  comX/sigX Streptococcus mutans UA159

43.791

83.607

0.366

Multiple sequence alignment