Detailed information NTG0342395

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: ETT46_RS01735
• Genome accession: NZ_CP035453
• Coordinates: 305035..305586 (+)
• Length: 183 a.a.
• NCBI ID: WP_136265115.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm100
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	306197..307319	305035..305586	flank	611

Gene organization within MGE regions

Location: 305035..307319

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT46_RS01735 (ETT46_01735)	comX/sigX/comX2/sigX2	305035..305586 (+)	552	WP_136265115.1	sigma-70 family RNA polymerase sigma factor	Regulator
ETT46_RS01740 (ETT46_01740)	-	306197..307319 (+)	1123	Protein_289	ISAs1-like element IS1548 family transposase	-

Sequence

Protein

• Length: 183 a.a.
• Molecular weight: 22255.05 Da
• Isoelectric Point: 10.0828

>NTDB_id=342395 ETT46_RS01735 WP_136265115.1 305035..305586(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm100]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
HRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide

• Length: 552 bp

>NTDB_id=342395 ETT46_RS01735 WP_136265115.1 305035..305586(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm100]
ATGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
CATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	99.454	100	0.995
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	99.454	100	0.995
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	98.907	100	0.989
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	98.907	100	0.989
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	98.907	100	0.989
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	98.907	100	0.989
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	48.667	81.967	0.399
comX	Streptococcus sobrinus strain NIDR 6715-7	46.104	84.153	0.388
comX/sigX	Streptococcus mutans UA159	43.791	83.607	0.366