Detailed information NTG0342301

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT48_RS04740
• Genome accession: NZ_CP035451
• Coordinates: 901046..901882 (+)
• Length: 278 a.a.
• NCBI ID: WP_063633159.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm230
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 896046..906882

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT48_RS04710 (ETT48_04705)	-	896599..896967 (+)	369	WP_002994996.1	hypothetical protein	-
ETT48_RS04715 (ETT48_04710)	-	897017..897928 (-)	912	WP_002995001.1	diacylglycerol kinase family protein	-
ETT48_RS04720 (ETT48_04715)	-	898045..898695 (-)	651	WP_002984629.1	hemolysin III family protein	-
ETT48_RS04725 (ETT48_04720)	-	898692..899132 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ETT48_RS04730 (ETT48_04725)	ylqF	899352..900200 (+)	849	WP_002995004.1	ribosome biogenesis GTPase YlqF	-
ETT48_RS04735 (ETT48_04730)	-	900190..900981 (+)	792	WP_002995007.1	ribonuclease HII	-
ETT48_RS04740 (ETT48_04735)	dprA	901046..901882 (+)	837	WP_063633159.1	DNA-processing protein DprA	Machinery gene
ETT48_RS04745 (ETT48_04740)	topA	901989..904118 (+)	2130	WP_011184520.1	type I DNA topoisomerase	-
ETT48_RS04750 (ETT48_04745)	trmFO	904253..905599 (+)	1347	WP_002995015.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31132.22 Da
• Isoelectric Point: 9.3978

>NTDB_id=342301 ETT48_RS04740 WP_063633159.1 901046..901882(+) (dprA) [Streptococcus pyogenes strain emm230]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKYYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFVVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=342301 ETT48_RS04740 WP_063633159.1 901046..901882(+) (dprA) [Streptococcus pyogenes strain emm230]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGTATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGTTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae D39	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae R6	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis SK321	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.353	100	0.594
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367