Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   ETT49_RS01430 Genome accession   NZ_CP035450
Coordinates   260600..261151 (+) Length   183 a.a.
NCBI ID   WP_136026554.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm93.4     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 255600..266151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT49_RS01430 (ETT49_01430) comX/sigX/comX2/sigX2 260600..261151 (+) 552 WP_136026554.1 sigma-70 family RNA polymerase sigma factor Regulator
  ETT49_RS01435 (ETT49_01435) - 261710..262237 (+) 528 WP_002991099.1 YqeG family HAD IIIA-type phosphatase -
  ETT49_RS01440 (ETT49_01440) yqeH 262237..263355 (+) 1119 WP_002991828.1 ribosome biogenesis GTPase YqeH -
  ETT49_RS01445 (ETT49_01445) yhbY 263380..263688 (+) 309 WP_002991094.1 ribosome assembly RNA-binding protein YhbY -
  ETT49_RS01450 (ETT49_01450) - 263757..264389 (+) 633 WP_014407306.1 nicotinate-nucleotide adenylyltransferase -
  ETT49_RS01455 (ETT49_01455) yqeK 264386..264979 (+) 594 WP_032464816.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ETT49_RS01460 (ETT49_01460) rsfS 265003..265356 (+) 354 WP_011017339.1 ribosome silencing factor -
  ETT49_RS01465 (ETT49_01465) - 265404..266147 (+) 744 WP_002991831.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22308.11 Da        Isoelectric Point: 10.0375

>NTDB_id=342232 ETT49_RS01430 WP_136026554.1 260600..261151(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm93.4]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIANLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=342232 ETT49_RS01430 WP_136026554.1 260600..261151(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm93.4]
GTGTCCTGTTGTTTTTTTGTGGTTCTTTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAACGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAACTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

49.333

81.967

0.404
  comX Streptococcus sobrinus strain NIDR 6715-7

46.104

84.153

0.388
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment