Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   ETT56_RS08300 Genome accession   NZ_CP035443
Coordinates   1603105..1603656 (-) Length   183 a.a.
NCBI ID   WP_080263242.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm58     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1598105..1608656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT56_RS08270 (ETT56_08260) rsfS 1598879..1599232 (-) 354 WP_011017339.1 ribosome silencing factor -
  ETT56_RS08275 (ETT56_08265) yqeK 1599256..1599849 (-) 594 WP_002985989.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ETT56_RS08280 (ETT56_08270) - 1599846..1600478 (-) 633 WP_011184179.1 nicotinate-nucleotide adenylyltransferase -
  ETT56_RS08285 (ETT56_08275) yhbY 1600547..1600855 (-) 309 WP_002991094.1 ribosome assembly RNA-binding protein YhbY -
  ETT56_RS08290 (ETT56_08280) yqeH 1600879..1601997 (-) 1119 WP_023078962.1 ribosome biogenesis GTPase YqeH -
  ETT56_RS08295 (ETT56_08285) - 1601997..1602524 (-) 528 WP_002991099.1 YqeG family HAD IIIA-type phosphatase -
  ETT56_RS08300 (ETT56_08290) comX/sigX/comX2/sigX2 1603105..1603656 (-) 552 WP_080263242.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22251.05 Da        Isoelectric Point: 10.1280

>NTDB_id=341878 ETT56_RS08300 WP_080263242.1 1603105..1603656(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm58]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLRLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=341878 ETT56_RS08300 WP_080263242.1 1603105..1603656(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm58]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTACGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

49.333

81.967

0.404
  comX Streptococcus sobrinus strain NIDR 6715-7

46.104

84.153

0.388
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment