Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   ETT59_RS07295 Genome accession   NZ_CP035440
Coordinates   1448251..1448841 (-) Length   196 a.a.
NCBI ID   WP_002985850.1    Uniprot ID   A0A9X8T4H8
Organism   Streptococcus pyogenes strain emm124     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1443251..1453841
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT59_RS07260 (ETT59_07255) - 1443431..1443823 (-) 393 WP_023609786.1 DUF5684 domain-containing protein -
  ETT59_RS07265 (ETT59_07260) rsmI 1443850..1444713 (-) 864 WP_020833286.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  ETT59_RS07270 (ETT59_07265) yabA 1444718..1445041 (-) 324 WP_053308587.1 DNA replication initiation control protein YabA -
  ETT59_RS09350 - 1445454..1445579 (-) 126 WP_002995110.1 hypothetical protein -
  ETT59_RS07280 (ETT59_07275) - 1445704..1446579 (-) 876 WP_010921931.1 DNA polymerase III subunit delta' -
  ETT59_RS07285 (ETT59_07280) tmk 1446597..1447232 (-) 636 WP_010921930.1 dTMP kinase -
  ETT59_RS07290 (ETT59_07285) - 1447481..1447756 (-) 276 WP_136276498.1 YlbG family protein -
  ETT59_RS07295 (ETT59_07290) clpP 1448251..1448841 (-) 591 WP_002985850.1 ATP-dependent Clp protease proteolytic subunit Regulator
  ETT59_RS07305 (ETT59_07300) upp 1449064..1449693 (-) 630 WP_002985854.1 uracil phosphoribosyltransferase -
  ETT59_RS07310 (ETT59_07305) - 1449861..1451495 (-) 1635 WP_136276499.1 polysaccharide biosynthesis protein -
  ETT59_RS07315 (ETT59_07310) - 1451583..1453028 (+) 1446 WP_136275270.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21648.88 Da        Isoelectric Point: 5.2834

>NTDB_id=341713 ETT59_RS07295 WP_002985850.1 1448251..1448841(-) (clpP) [Streptococcus pyogenes strain emm124]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide


Download         Length: 591 bp        

>NTDB_id=341713 ETT59_RS07295 WP_002985850.1 1448251..1448841(-) (clpP) [Streptococcus pyogenes strain emm124]
ATGATTCCTGTTGTTATTGAACAAACTAGCCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTAAAAGACCGTAT
TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA
ACACGAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC
TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA
AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGCACAGGCGGTGGCACGCAACAAA
CGGATATGGCTATCGCAGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCGCAAAATGCTGGAAAA
ACGATTAAACAAATCCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA
TGAAATCATGGAAAACAACGAACTAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pyogenes MGAS315

100

100

1
  clpP Streptococcus pyogenes JRS4

100

100

1
  clpP Streptococcus mutans UA159

90.816

100

0.908
  clpP Streptococcus pneumoniae Rx1

90.769

99.49

0.903
  clpP Streptococcus pneumoniae D39

90.769

99.49

0.903
  clpP Streptococcus pneumoniae R6

90.769

99.49

0.903
  clpP Streptococcus pneumoniae TIGR4

90.769

99.49

0.903
  clpP Streptococcus thermophilus LMG 18311

89.796

100

0.898
  clpP Streptococcus thermophilus LMD-9

89.796

100

0.898
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

86.224

100

0.862
  clpP Lactococcus lactis subsp. cremoris KW2

85.714

100

0.857
  clpP Bacillus subtilis subsp. subtilis str. 168

57.143

100

0.571
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.995

98.469

0.561

Multiple sequence alignment