Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   ETT59_RS05190 Genome accession   NZ_CP035440
Coordinates   1026207..1026395 (-) Length   62 a.a.
NCBI ID   WP_136105726.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm124     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1026207..1043770 1026207..1026395 within 0


Gene organization within MGE regions


Location: 1026207..1043770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT59_RS05190 (ETT59_05190) prx 1026207..1026395 (-) 189 WP_136105726.1 Paratox Regulator
  ETT59_RS05195 (ETT59_05195) - 1027099..1027317 (-) 219 Protein_935 SH3 domain-containing protein -
  ETT59_RS05200 (ETT59_05200) - 1027406..1027645 (-) 240 WP_014411882.1 helix-turn-helix transcriptional regulator -
  ETT59_RS05205 (ETT59_05205) - 1027742..1028521 (+) 780 WP_085613681.1 hypothetical protein -
  ETT59_RS05210 (ETT59_05210) - 1028655..1028813 (-) 159 WP_085613682.1 hypothetical protein -
  ETT59_RS05215 (ETT59_05215) - 1029186..1029974 (+) 789 WP_111676459.1 S24 family peptidase -
  ETT59_RS05220 (ETT59_05220) - 1029984..1030289 (+) 306 WP_011106738.1 membrane protein -
  ETT59_RS05225 (ETT59_05225) - 1030413..1031552 (+) 1140 WP_002990094.1 site-specific integrase -
  ETT59_RS05230 (ETT59_05230) rfbB 1031646..1032686 (-) 1041 WP_010922196.1 dTDP-glucose 4,6-dehydratase -
  ETT59_RS05235 (ETT59_05235) - 1032930..1033523 (-) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  ETT59_RS05240 (ETT59_05240) rfbA 1033523..1034392 (-) 870 WP_002992970.1 glucose-1-phosphate thymidylyltransferase RfbA -
  ETT59_RS05245 (ETT59_05245) - 1034450..1035559 (-) 1110 WP_136305947.1 FAD-binding oxidoreductase -
  ETT59_RS05250 (ETT59_05250) - 1035599..1036387 (-) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  ETT59_RS05255 (ETT59_05255) - 1036377..1037063 (-) 687 WP_002990104.1 tRNA (adenine(22)-N(1))-methyltransferase TrmK -
  ETT59_RS05260 (ETT59_05260) nth 1037135..1037791 (-) 657 WP_010922193.1 endonuclease III -
  ETT59_RS05265 (ETT59_05265) - 1037788..1038471 (-) 684 WP_053308318.1 DnaD domain-containing protein -
  ETT59_RS05270 (ETT59_05270) - 1038552..1039070 (-) 519 WP_002990109.1 adenine phosphoribosyltransferase -
  ETT59_RS05275 (ETT59_05275) recJ 1039220..1041430 (-) 2211 WP_136047837.1 single-stranded-DNA-specific exonuclease RecJ -
  ETT59_RS05280 (ETT59_05280) - 1041427..1042191 (-) 765 WP_002984893.1 SDR family oxidoreductase -
  ETT59_RS05285 (ETT59_05285) rnz 1042191..1043120 (-) 930 WP_136305946.1 ribonuclease Z -
  ETT59_RS05290 (ETT59_05290) - 1043135..1043770 (-) 636 WP_002990114.1 cystathionine beta-lyase -

Sequence

Protein


Download         Length: 62 a.a.        Molecular weight: 7238.14 Da        Isoelectric Point: 3.9282

>NTDB_id=341703 ETT59_RS05190 WP_136105726.1 1026207..1026395(-) (prx) [Streptococcus pyogenes strain emm124]
MLTYDEFKQAIDNGYITADAVMIVRKNGQIFDYVLPHEEIRDWEVVTIERISDVMAELSESE

Nucleotide


Download         Length: 189 bp        

>NTDB_id=341703 ETT59_RS05190 WP_136105726.1 1026207..1026395(-) (prx) [Streptococcus pyogenes strain emm124]
ATGCTAACATACGACGAATTTAAGCAAGCGATTGACAATGGATATATCACAGCAGACGCAGTAATGATCGTGCGCAAGAA
CGGACAGATTTTTGATTATGTGTTGCCGCATGAGGAGATAAGAGATTGGGAGGTTGTGACAATCGAGCGGATATCAGATG
TTATGGCAGAACTTTCTGAGTCTGAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

75.862

93.548

0.71
  prx Streptococcus pyogenes MGAS315

74.576

95.161

0.71
  prx Streptococcus pyogenes MGAS315

70

96.774

0.677
  prx Streptococcus pyogenes MGAS8232

71.186

95.161

0.677
  prx Streptococcus pyogenes MGAS315

85.714

67.742

0.581
  prx Streptococcus pyogenes MGAS315

82.927

66.129

0.548
  prx Streptococcus pyogenes MGAS315

73.81

67.742

0.5

Multiple sequence alignment