Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   ETT60_RS01490 Genome accession   NZ_CP035439
Coordinates   273439..273990 (+) Length   183 a.a.
NCBI ID   WP_129284263.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm77     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 268439..278990
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT60_RS01490 (ETT60_01490) comX/sigX/comX2/sigX2 273439..273990 (+) 552 WP_129284263.1 sigma-70 family RNA polymerase sigma factor Regulator
  ETT60_RS01495 (ETT60_01495) - 274549..275076 (+) 528 WP_002991099.1 YqeG family HAD IIIA-type phosphatase -
  ETT60_RS01500 (ETT60_01500) yqeH 275076..276194 (+) 1119 WP_015016688.1 ribosome biogenesis GTPase YqeH -
  ETT60_RS01505 (ETT60_01505) yhbY 276219..276527 (+) 309 WP_111685182.1 ribosome assembly RNA-binding protein YhbY -
  ETT60_RS01510 (ETT60_01510) - 276596..277228 (+) 633 WP_014407306.1 nicotinate-nucleotide adenylyltransferase -
  ETT60_RS01515 (ETT60_01515) yqeK 277225..277818 (+) 594 WP_129284405.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ETT60_RS01520 (ETT60_01520) rsfS 277842..278195 (+) 354 WP_011017339.1 ribosome silencing factor -
  ETT60_RS01525 (ETT60_01525) - 278243..278986 (+) 744 WP_161761883.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22262.03 Da        Isoelectric Point: 9.9399

>NTDB_id=341633 ETT60_RS01490 WP_129284263.1 273439..273990(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm77]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEEHL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=341633 ETT60_RS01490 WP_129284263.1 273439..273990(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm77]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCATTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

49.333

81.967

0.404
  comX Streptococcus sobrinus strain NIDR 6715-7

46.104

84.153

0.388
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment