Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   ETT69_RS08325 Genome accession   NZ_CP035430
Coordinates   1620434..1620985 (-) Length   183 a.a.
NCBI ID   WP_136019468.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm55     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1615434..1625985
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT69_RS08300 (ETT69_08290) - 1616793..1617638 (+) 846 WP_136019466.1 mechanosensitive ion channel family protein -
  ETT69_RS08305 (ETT69_08295) - 1617710..1618270 (-) 561 WP_168389120.1 TIGR01440 family protein -
  ETT69_RS08310 (ETT69_08300) - 1618284..1618754 (-) 471 WP_002988139.1 ECF transporter S component -
  ETT69_RS08315 (ETT69_08305) - 1618744..1619508 (-) 765 WP_032465223.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  ETT69_RS08320 (ETT69_08310) truA 1619498..1620247 (-) 750 WP_002988132.1 tRNA pseudouridine(38-40) synthase TruA -
  ETT69_RS08325 (ETT69_08315) comX/sigX/comX2/sigX2 1620434..1620985 (-) 552 WP_136019468.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22309.14 Da        Isoelectric Point: 10.1280

>NTDB_id=341186 ETT69_RS08325 WP_136019468.1 1620434..1620985(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm55]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENRLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=341186 ETT69_RS08325 WP_136019468.1 1620434..1620985(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm55]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCGATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

49.333

81.967

0.404
  comX Streptococcus sobrinus strain NIDR 6715-7

46.104

84.153

0.388
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment