Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   ETT69_RS01740 Genome accession   NZ_CP035430
Coordinates   311863..312414 (+) Length   183 a.a.
NCBI ID   WP_136019468.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm55     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 306863..317414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT69_RS01740 (ETT69_01740) comX/sigX/comX2/sigX2 311863..312414 (+) 552 WP_136019468.1 sigma-70 family RNA polymerase sigma factor Regulator
  ETT69_RS09855 - 313071..313781 (+) 711 WP_227868652.1 transposase -
  ETT69_RS09860 - 313679..314311 (+) 633 WP_247275460.1 transposase -
  ETT69_RS01750 (ETT69_01750) - 314553..315080 (+) 528 WP_168389096.1 YqeG family HAD IIIA-type phosphatase -
  ETT69_RS01755 (ETT69_01755) yqeH 315080..316198 (+) 1119 WP_015016688.1 ribosome biogenesis GTPase YqeH -
  ETT69_RS01760 (ETT69_01760) yhbY 316223..316531 (+) 309 WP_002991094.1 ribosome assembly RNA-binding protein YhbY -
  ETT69_RS01765 (ETT69_01765) - 316600..317232 (+) 633 WP_136019216.1 nicotinate-nucleotide adenylyltransferase -

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22309.14 Da        Isoelectric Point: 10.1280

>NTDB_id=341158 ETT69_RS01740 WP_136019468.1 311863..312414(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm55]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENRLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=341158 ETT69_RS01740 WP_136019468.1 311863..312414(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain emm55]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCGATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

49.333

81.967

0.404
  comX Streptococcus sobrinus strain NIDR 6715-7

46.104

84.153

0.388
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment