Detailed information NTG0341006

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT72_RS05085
• Genome accession: NZ_CP035427
• Coordinates: 955438..956274 (+)
• Length: 278 a.a.
• NCBI ID: WP_032464378.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm74
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 950438..961274

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT72_RS05055 (ETT72_05050)	-	950926..951360 (+)	435	WP_136275021.1	hypothetical protein	-
ETT72_RS05060 (ETT72_05055)	-	951410..952321 (-)	912	WP_136292358.1	diacylglycerol kinase family protein	-
ETT72_RS05065 (ETT72_05060)	-	952438..953088 (-)	651	WP_032464375.1	hemolysin III family protein	-
ETT72_RS05070 (ETT72_05065)	-	953085..953525 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
ETT72_RS05075 (ETT72_05070)	ylqF	953744..954592 (+)	849	WP_032464376.1	ribosome biogenesis GTPase YlqF	-
ETT72_RS05080 (ETT72_05075)	-	954582..955373 (+)	792	WP_032464377.1	ribonuclease HII	-
ETT72_RS05085 (ETT72_05080)	dprA	955438..956274 (+)	837	WP_032464378.1	DNA-processing protein DprA	Machinery gene
ETT72_RS05090 (ETT72_05085)	topA	956381..958510 (+)	2130	WP_032464379.1	type I DNA topoisomerase	-
ETT72_RS05095 (ETT72_05090)	trmFO	958645..959991 (+)	1347	WP_110410793.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31088.08 Da
• Isoelectric Point: 9.0513

>NTDB_id=341006 ETT72_RS05085 WP_032464378.1 955438..956274(+) (dprA) [Streptococcus pyogenes strain emm74]
MNHFELYKLKKARLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=341006 ETT72_RS05085 WP_032464378.1 955438..956274(+) (dprA) [Streptococcus pyogenes strain emm74]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTAGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Acinetobacter baumannii strain A118	35.395	100	0.371
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367