Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   CPH39_RS09760 Genome accession   NZ_CP043542
Coordinates   2034741..2036573 (+) Length   610 a.a.
NCBI ID   WP_053884504.1    Uniprot ID   -
Organism   Escherichia coli strain F2_81     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2029741..2041573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CPH39_RS09725 (CPH39_09860) dcyD 2029967..2030953 (+) 987 WP_001128214.1 D-cysteine desulfhydrase -
  CPH39_RS09730 (CPH39_09865) tcyL 2030968..2031636 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  CPH39_RS09735 (CPH39_09870) tcyN 2031633..2032385 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  CPH39_RS09740 (CPH39_09875) sdiA 2032615..2033337 (+) 723 WP_053884505.1 transcriptional regulator SdiA -
  CPH39_RS09745 (CPH39_09880) yecF 2033405..2033629 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  CPH39_RS09750 (CPH39_09885) yecU 2033616..2033792 (-) 177 WP_000590344.1 protein YecU -
  CPH39_RS26820 (CPH39_09890) - 2033830..2033946 (-) 117 WP_001302039.1 hypothetical protein -
  CPH39_RS09755 (CPH39_09895) letA 2034088..2034744 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  CPH39_RS09760 (CPH39_09900) uvrC 2034741..2036573 (+) 1833 WP_053884504.1 excinuclease ABC subunit UvrC Machinery gene
  CPH39_RS09765 (CPH39_09905) pgsA 2036630..2037178 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  CPH39_RS09785 (CPH39_09925) yecA 2037828..2038493 (+) 666 WP_000847882.1 UPF0149 family protein YecA -
  CPH39_RS09790 (CPH39_09930) tyrP 2038555..2039766 (-) 1212 WP_053884503.1 tyrosine transporter TyrP -
  CPH39_RS09795 (CPH39_09935) yecH 2039957..2040196 (+) 240 WP_000377224.1 YecH family metal-binding protein -
  CPH39_RS09800 (CPH39_09940) ftnA 2040234..2040731 (-) 498 WP_000917208.1 non-heme ferritin -
  CPH39_RS09805 (CPH39_09945) yecR 2040903..2041226 (-) 324 WP_001578509.1 YecR-like lipofamily protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68214.11 Da        Isoelectric Point: 9.3685

>NTDB_id=338294 CPH39_RS09760 WP_053884504.1 2034741..2036573(+) (uvrC) [Escherichia coli strain F2_81]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWLLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=338294 CPH39_RS09760 WP_053884504.1 2034741..2036573(+) (uvrC) [Escherichia coli strain F2_81]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCTGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTACTACGCGATGATAAATCTTATCCCTTTATCTTCCT
GAGTGGCGATACCCATCCGCGTCTGGCGATGCATCGTGGTGCAAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCTGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAATTCGTTTCCAATACAGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGTGGCGATAGAGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGGCTTACAGCACTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACTGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TCGACGACAGTAAGATCCCGGATGTGATACTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACATGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGCCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTTGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

Helix-hairpin-helix domain (HHH_5)

(558-604)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374

Multiple sequence alignment