Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   MGAS2221_RS07160 Genome accession   NZ_CP043530
Coordinates   1408734..1408913 (-) Length   59 a.a.
NCBI ID   WP_002988813.1    Uniprot ID   Q5YAB1
Organism   Streptococcus pyogenes strain MGAS2221     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context

Location: 1403734..1413913
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS2221_RS07140 (MGAS2221_1425) - 1406014..1406316 (-) 303 WP_002983488.1 YlxQ-related RNA-binding protein -
  MGAS2221_RS07145 (MGAS2221_1426) - 1406309..1406605 (-) 297 WP_002983486.1 YlxR family protein -
  MGAS2221_RS07150 (MGAS2221_1427) nusA 1406621..1407778 (-) 1158 WP_002988817.1 transcription termination factor NusA -
  MGAS2221_RS07155 (MGAS2221_1428) rimP 1407953..1408489 (-) 537 WP_002988815.1 ribosome maturation factor RimP -
  MGAS2221_RS07160 (MGAS2221_1429) prx 1408734..1408913 (-) 180 WP_002988813.1 hypothetical protein Regulator
  MGAS2221_RS07165 (MGAS2221_1430) sda1 1409152..1410324 (+) 1173 WP_002988811.1 streptodornase Sda1 -
  MGAS2221_RS07170 (MGAS2221_1431) - 1410440..1411636 (-) 1197 WP_002988807.1 glucosaminidase domain-containing protein -
  MGAS2221_RS07175 (MGAS2221_1433) - 1411747..1411932 (-) 186 WP_002988802.1 holin -
  MGAS2221_RS07180 (MGAS2221_1434) - 1411929..1412228 (-) 300 WP_002988799.1 hypothetical protein -
  MGAS2221_RS07185 (MGAS2221_1435) - 1412239..1412859 (-) 621 WP_002988797.1 hypothetical protein -
  MGAS2221_RS07190 (MGAS2221_1436) - 1412862..1413023 (-) 162 WP_002988795.1 hypothetical protein -

Sequence

Protein


Download         Length: 59 a.a.        Molecular weight: 6798.70 Da        Isoelectric Point: 4.2542

>NTDB_id=338148 MGAS2221_RS07160 WP_002988813.1 1408734..1408913(-) (prx) [Streptococcus pyogenes strain MGAS2221]
MLTYDEFKQAIDHGYITGDTVAIVRKNGQIFDYVLPHEKVKNGEVVTDEKVEEVLMELE

Nucleotide


Download         Length: 180 bp        

>NTDB_id=338148 MGAS2221_RS07160 WP_002988813.1 1408734..1408913(-) (prx) [Streptococcus pyogenes strain MGAS2221]
ATGCTAACATACGACGAATTTAAGCAAGCAATCGACCATGGGTATATCACAGGAGACACAGTAGCGATTGTGCGCAAAAA
CGGACAGATCTTTGATTATGTGTTGCCACATGAGAAAGTAAAGAATGGAGAAGTTGTGACAGATGAAAAAGTGGAAGAAG
TGTTGATGGAATTGGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5YAB1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS8232

91.379

98.305

0.898
  prx Streptococcus pyogenes MGAS315

87.931

98.305

0.864
  prx Streptococcus pyogenes MGAS315

84.746

100

0.847
  prx Streptococcus pyogenes MGAS315

74.576

100

0.746
  prx Streptococcus pyogenes MGAS315

86.047

72.881

0.627
  prx Streptococcus pyogenes MGAS315

90.244

69.492

0.627
  prx Streptococcus pyogenes MGAS315

80.952

71.186

0.576

Multiple sequence alignment