Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   MGAS2221_RS05895 Genome accession   NZ_CP043530
Coordinates   1169056..1169238 (-) Length   60 a.a.
NCBI ID   WP_011017964.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS2221     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context

Location: 1164056..1174238
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS2221_RS05880 (MGAS2221_1175) - 1164494..1165189 (-) 696 WP_002983928.1 phosphoglycerate mutase -
  MGAS2221_RS05885 (MGAS2221_1176) - 1165428..1166363 (+) 936 WP_010922443.1 dihydroorotate oxidase -
  MGAS2221_RS05890 (MGAS2221_1177) - 1166663..1168525 (-) 1863 WP_011285610.1 heavy metal translocating P-type ATPase -
  MGAS2221_RS05895 (MGAS2221_1178) prx 1169056..1169238 (-) 183 WP_011017964.1 hypothetical protein Regulator
  MGAS2221_RS05900 (MGAS2221_1179) sda3 1169477..1170277 (+) 801 WP_011285611.1 streptodornase Sda3 -
  MGAS2221_RS05905 (MGAS2221_1180) - 1170548..1170982 (+) 435 WP_011017966.1 hypothetical protein -
  MGAS2221_RS05910 (MGAS2221_1181) - 1171052..1172257 (-) 1206 WP_010922446.1 glucosaminidase domain-containing protein -
  MGAS2221_RS05915 (MGAS2221_1182) - 1172373..1172600 (-) 228 WP_003058873.1 phage holin -
  MGAS2221_RS05920 (MGAS2221_1183) - 1172597..1172872 (-) 276 WP_002987582.1 hypothetical protein -
  MGAS2221_RS05925 (MGAS2221_1184) - 1172882..1173499 (-) 618 WP_011285613.1 DUF1366 domain-containing protein -
  MGAS2221_RS05930 (MGAS2221_1185) - 1173496..1173933 (-) 438 WP_011285614.1 DUF1617 family protein -

Sequence

Protein


Download         Length: 60 a.a.        Molecular weight: 6841.79 Da        Isoelectric Point: 4.5183

>NTDB_id=338135 MGAS2221_RS05895 WP_011017964.1 1169056..1169238(-) (prx) [Streptococcus pyogenes strain MGAS2221]
MLTYDEFKQAIDNGYIAGDTVAIVRKDGQIFDYVLPHEKVKNGEVVTKEKVEEVLVELSR

Nucleotide


Download         Length: 183 bp        

>NTDB_id=338135 MGAS2221_RS05895 WP_011017964.1 1169056..1169238(-) (prx) [Streptococcus pyogenes strain MGAS2221]
ATGCTAACATACGACGAGTTTAAGCAAGCGATTGACAATGGATATATCGCAGGCGATACAGTAGCGATCGTGCGTAAAGA
CGGACAGATTTTTGATTATGTGTTGCCACATGAGAAAGTAAAGAATGGAGAAGTTGTGACTAAGGAAAAAGTGGAAGAGG
TGCTGGTGGAGCTTTCGAGATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS8232

100

100

1
  prx Streptococcus pyogenes MGAS315

85

100

0.85
  prx Streptococcus pyogenes MGAS315

80

100

0.8
  prx Streptococcus pyogenes MGAS315

73.333

100

0.733
  prx Streptococcus pyogenes MGAS315

90.244

68.333

0.617
  prx Streptococcus pyogenes MGAS315

83.721

71.667

0.6
  prx Streptococcus pyogenes MGAS315

78.571

70

0.55