Detailed information NTG0337778

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH29_RS09225
• Genome accession: NZ_CP035251
• Coordinates: 1841643..1842653 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901935
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1836643..1847653

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH29_RS09200 (EQH29_09775)	-	1836708..1837922 (-)	1215	WP_047475499.1	pyridoxal phosphate-dependent aminotransferase	-
EQH29_RS09205 (EQH29_09780)	-	1838078..1838372 (-)	295	Protein_1820	hypothetical protein	-
EQH29_RS09210 (EQH29_09785)	-	1838534..1838986 (+)	453	WP_000079148.1	universal stress protein	-
EQH29_RS09215 (EQH29_09790)	-	1839021..1840409 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
EQH29_RS09220 (EQH29_09795)	-	1840475..1841437 (+)	963	WP_001124777.1	asparaginase	-
EQH29_RS09225 (EQH29_09800)	ccpA	1841643..1842653 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH29_RS09230 (EQH29_09805)	-	1843078..1843677 (-)	600	WP_000866719.1	response regulator transcription factor	-
EQH29_RS09235 (EQH29_09810)	-	1843679..1844776 (-)	1098	WP_000893546.1	sensor histidine kinase	-
EQH29_RS09240 (EQH29_09815)	-	1844776..1845513 (-)	738	WP_000832834.1	ABC transporter permease	-
EQH29_RS09245 (EQH29_09820)	-	1845515..1846399 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
EQH29_RS09250 (EQH29_09825)	-	1846386..1846580 (-)	195	WP_000820180.1	hypothetical protein	-
EQH29_RS09255 (EQH29_09830)	-	1846577..1846783 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=337778 EQH29_RS09225 WP_000990607.1 1841643..1842653(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901935]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=337778 EQH29_RS09225 WP_000990607.1 1841643..1842653(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901935]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568