Detailed information NTG0337438

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: EQH34_RS05860
• Genome accession: NZ_CP035246
• Coordinates: 1179083..1179733 (-)
• Length: 216 a.a.
• NCBI ID: WP_000387339.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901941
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1174083..1184733

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH34_RS05840 (EQH34_06205)	-	1174687..1175871 (-)	1185	WP_000652066.1	ABC transporter permease	-
EQH34_RS05845 (EQH34_06210)	-	1175868..1176461 (-)	594	WP_000933549.1	ATP-binding cassette domain-containing protein	-
EQH34_RS05850 (EQH34_06215)	-	1176493..1176717 (-)	225	WP_001850593.1	hypothetical protein	-
EQH34_RS05855 (EQH34_06220)	comEC/celB	1176859..1179099 (-)	2241	WP_000942397.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EQH34_RS05860 (EQH34_06225)	comEA/celA/cilE	1179083..1179733 (-)	651	WP_000387339.1	ComEA family DNA-binding protein	Machinery gene
EQH34_RS05865 (EQH34_06230)	-	1179801..1180370 (-)	570	WP_000443776.1	GNAT family N-acetyltransferase	-
EQH34_RS05870	ald	1180547..1181658 (+)	1112	Protein_1175	alanine dehydrogenase	-
EQH34_RS05875 (EQH34_06255)	-	1181959..1182284 (-)	326	Protein_1176	TfoX/Sxy family protein	-
EQH34_RS05880 (EQH34_06260)	-	1182287..1182787 (-)	501	WP_000566982.1	GNAT family N-acetyltransferase	-
EQH34_RS05885 (EQH34_06270)	-	1182980..1183948 (-)	969	WP_000658183.1	PhoH family protein	-
EQH34_RS05890 (EQH34_06275)	-	1184034..1184249 (-)	216	WP_001232082.1	YozE family protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23228.71 Da
• Isoelectric Point: 6.9977

>NTDB_id=337438 EQH34_RS05860 WP_000387339.1 1179083..1179733(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain TVO_1901941]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKKEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=337438 EQH34_RS05860 WP_000387339.1 1179083..1179733(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain TVO_1901941]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGAAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	99.537	100	0.995
comEA/celA/cilE	Streptococcus pneumoniae D39	99.537	100	0.995
comEA/celA/cilE	Streptococcus pneumoniae R6	99.537	100	0.995
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	96.759	100	0.968
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	89.815	100	0.898
comEA	Lactococcus lactis subsp. cremoris KW2	43.172	100	0.454
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366
comEA	Latilactobacillus sakei subsp. sakei 23K	33.476	100	0.361