Detailed information NTG0337200

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: EQH37_RS04595
• Genome accession: NZ_CP035243
• Coordinates: 909242..909892 (+)
• Length: 216 a.a.
• NCBI ID: WP_000387336.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901946
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 904242..914892

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH37_RS04565 (EQH37_04845)	-	904725..904940 (+)	216	WP_001232082.1	YozE family protein	-
EQH37_RS04570 (EQH37_04850)	-	905026..905994 (+)	969	WP_000658191.1	PhoH family protein	-
EQH37_RS04575 (EQH37_04860)	-	906187..906687 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
EQH37_RS04580 (EQH37_04865)	-	906690..907064 (+)	375	Protein_919	TfoX/Sxy family protein	-
EQH37_RS04585 (EQH37_04870)	ald	907318..908428 (-)	1111	Protein_920	alanine dehydrogenase	-
EQH37_RS04590 (EQH37_04875)	-	908605..909174 (+)	570	WP_000443749.1	GNAT family N-acetyltransferase	-
EQH37_RS04595 (EQH37_04880)	comEA/celA/cilE	909242..909892 (+)	651	WP_000387336.1	ComEA family DNA-binding protein	Machinery gene
EQH37_RS04600 (EQH37_04885)	comEC/celB	909876..912116 (+)	2241	WP_054366115.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EQH37_RS04605 (EQH37_04890)	-	912295..912483 (+)	189	WP_001809102.1	hypothetical protein	-
EQH37_RS04610 (EQH37_04895)	-	912515..913102 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
EQH37_RS04615 (EQH37_04900)	-	913106..914287 (+)	1182	WP_000655951.1	membrane protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23189.54 Da
• Isoelectric Point: 5.5171

>NTDB_id=337200 EQH37_RS04595 WP_000387336.1 909242..909892(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain TVO_1901946]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=337200 EQH37_RS04595 WP_000387336.1 909242..909892(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain TVO_1901946]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTAAAGGAAACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	99.074	100	0.991
comEA/celA/cilE	Streptococcus pneumoniae D39	99.074	100	0.991
comEA/celA/cilE	Streptococcus pneumoniae R6	99.074	100	0.991
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	97.222	100	0.972
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	91.204	100	0.912
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366
comEA	Latilactobacillus sakei subsp. sakei 23K	33.476	100	0.361