Detailed information NTG0336245

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: EQW70_RS18595
• Genome accession: NZ_CP035226
• Coordinates: 3516547..3517140 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis strain SRCM103517
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3511547..3522140

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQW70_RS18565 (EQW70_18565)	aspP	3512519..3514081 (+)	1563	WP_003228228.1	aspartate/proton symporter AspP	-
EQW70_RS18570 (EQW70_18570)	-	3514176..3514760 (+)	585	WP_031315347.1	TetR family transcriptional regulator	-
EQW70_RS18575 (EQW70_18575)	psmA	3514842..3515177 (+)	336	WP_014480966.1	SMR family transporter	-
EQW70_RS18580 (EQW70_18580)	psmB	3515177..3515497 (+)	321	WP_003228222.1	QacE family quaternary ammonium compound efflux SMR transporter	-
EQW70_RS18585 (EQW70_18585)	yvdQ	3515533..3516045 (-)	513	WP_072175092.1	DUF3231 family protein	-
EQW70_RS18595 (EQW70_18595)	clpP	3516547..3517140 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
EQW70_RS18600 (EQW70_18600)	pgmB	3517202..3517876 (-)	675	WP_128740748.1	beta-phosphoglucomutase	-
EQW70_RS18605 (EQW70_18605)	malL	3517873..3519558 (-)	1686	WP_128740749.1	oligo-1,6-glucosidase	-
EQW70_RS18610 (EQW70_18610)	mdxK	3519551..3521824 (-)	2274	WP_128740750.1	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=336245 EQW70_RS18595 WP_003228214.1 3516547..3517140(+) (clpP) [Bacillus subtilis strain SRCM103517]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=336245 EQW70_RS18595 WP_003228214.1 3516547..3517140(+) (clpP) [Bacillus subtilis strain SRCM103517]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGATAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538