Detailed information NTG0033436

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SZO_RS00285
• Genome accession: NC_012470
• Coordinates: 49236..50150 (+)
• Length: 304 a.a.
• NCBI ID: WP_012677204.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 44236..55150

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SZO_RS00265 (SZO_00330)	purE	45261..45749 (+)	489	WP_012677200.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
SZO_RS00270 (SZO_00340)	purK	45736..46809 (+)	1074	WP_012677201.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
SZO_RS00275 (SZO_00350)	-	46824..47048 (+)	225	WP_012677202.1	hypothetical protein	-
SZO_RS00280 (SZO_00380)	purB	47645..48937 (+)	1293	WP_041790267.1	adenylosuccinate lyase	-
SZO_RS00285 (SZO_00390)	comR	49236..50150 (+)	915	WP_012677204.1	helix-turn-helix domain-containing protein	Regulator
SZO_RS10925	comS	50233..50331 (+)	99	WP_021320241.1	quorum-sensing system DWW-type pheromone	Regulator
SZO_RS00290 (SZO_00400)	ruvB	50365..51372 (+)	1008	WP_012677205.1	Holliday junction branch migration DNA helicase RuvB	-
SZO_RS00295 (SZO_00410)	-	51613..52071 (+)	459	WP_012677206.1	low molecular weight protein-tyrosine-phosphatase	-
SZO_RS00300 (SZO_00420)	-	52077..52478 (+)	402	WP_012514718.1	MORN repeat-containing protein	-
SZO_RS00305 (SZO_00430)	-	52475..54256 (+)	1782	WP_012677207.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35789.36 Da
• Isoelectric Point: 4.5886

>NTDB_id=33436 SZO_RS00285 WP_012677204.1 49236..50150(+) (comR) [Streptococcus equi subsp. zooepidemicus]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVFIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFNEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIAGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKPEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWGKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=33436 SZO_RS00285 WP_012677204.1 49236..50150(+) (comR) [Streptococcus equi subsp. zooepidemicus]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTGCGGTATCAGAAAAAAATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTGGCACGAATAGAACTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTTTATTG
CTAAGGCTTTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTACCGAAGCGCTATAAGGAGCTTAAA
TATTTGATTTTAAGAACACCGACCTATATGGACGATGACAAATTAAAGCTGCGAGAAGAGCAATTTAACGAAATTTTTGA
AGATTATTATGACCAGTTGCCAGAGGAAGAAAAGCTTGTGGTGGATTGCTTGCAGTCCATAATGGATACGTTATTAACCG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAAACAAAAAGTAAGACTCAATTTAGAGAGAATGAT
CTCATTCTTATTGAGCTGTATTTAGCGTACCTCGACATTGCAGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTGTTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATTGTCAATAAAATAGCTATAG
GAATTTCCTCGTTGAGCATCAAAAACAATAAGCCGGAGATTCTTGAGAAGGTTATTGTACTTAGTCAAAAAATTATCCTC
AAGACTCAAGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATATGCTCTAATGAAGAAAAAAGACATAGA
AATGGCCAAAAAATGCTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTGGAAAAGAAATTGAGAG
AAGAATGGGGTAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix domain (HTH_19) (6-69)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.257	99.671	0.74
comR	Streptococcus pyogenes MGAS315	54.485	99.013	0.539
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.724	95.395	0.493
comR	Streptococcus mutans UA159	48.829	98.355	0.48
comR	Streptococcus suis P1/7	38.255	98.026	0.375
comR	Streptococcus suis D9	37.542	99.013	0.372
comR	Streptococcus suis 05ZYH33	38.305	97.039	0.372