Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SPT_RS06195 Genome accession   NC_012469
Coordinates   1190792..1191442 (-) Length   216 a.a.
NCBI ID   WP_000387336.1    Uniprot ID   -
Organism   Streptococcus pneumoniae Taiwan19F-14     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1185792..1196442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPT_RS06175 (SPT_1245) - 1186394..1187578 (-) 1185 WP_000655961.1 membrane protein -
  SPT_RS06180 (SPT_1246) - 1187582..1188169 (-) 588 WP_000939881.1 ATP-binding cassette domain-containing protein -
  SPT_RS13365 - 1188202..1188419 (-) 218 Protein_1192 hypothetical protein -
  SPT_RS06190 (SPT_1247) comEC/celB 1188568..1190808 (-) 2241 WP_000942405.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SPT_RS06195 (SPT_1248) comEA/celA/cilE 1190792..1191442 (-) 651 WP_000387336.1 ComEA family DNA-binding protein Machinery gene
  SPT_RS06200 (SPT_1249) - 1191510..1192079 (-) 570 WP_000443774.1 GNAT family N-acetyltransferase -
  SPT_RS13020 (SPT_1252) ald 1192256..1193367 (+) 1112 Protein_1196 alanine dehydrogenase -
  SPT_RS06220 (SPT_1253) - 1193668..1193994 (-) 327 Protein_1197 TfoX/Sxy family protein -
  SPT_RS06225 (SPT_1254) - 1193997..1194497 (-) 501 WP_000566986.1 GNAT family N-acetyltransferase -
  SPT_RS06230 (SPT_1255) - 1194690..1195658 (-) 969 WP_000658198.1 PhoH family protein -
  SPT_RS06235 (SPT_1257) - 1195744..1195959 (-) 216 WP_001232081.1 YozE family protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23189.54 Da        Isoelectric Point: 5.5171

>NTDB_id=33383 SPT_RS06195 WP_000387336.1 1190792..1191442(-) (comEA/celA/cilE) [Streptococcus pneumoniae Taiwan19F-14]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=33383 SPT_RS06195 WP_000387336.1 1190792..1191442(-) (comEA/celA/cilE) [Streptococcus pneumoniae Taiwan19F-14]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTAAAGGAAACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae D39

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae R6

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

97.222

100

0.972
  comEA/celA/cilE Streptococcus mitis NCTC 12261

95.833

100

0.958
  comEA/celA/cilE Streptococcus mitis SK321

91.204

100

0.912
  comEA Lactococcus lactis subsp. cremoris KW2

43.612

100

0.458
  comEA Bacillus subtilis subsp. subtilis str. 168

41.579

87.963

0.366
  comEA Latilactobacillus sakei subsp. sakei 23K

33.476

100

0.361

Multiple sequence alignment