Detailed information NTG0033298

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: SP70585_RS03900
• Genome accession: NC_012468
• Coordinates: 723899..724489 (+)
• Length: 196 a.a.
• NCBI ID: WP_000613481.1
• Uniprot ID: C1C691
• Organism: Streptococcus pneumoniae 70585
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 718899..729489

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP70585_RS03870 (SP70585_0786)	-	719284..719739 (-)	456	WP_041170956.1	8-oxo-dGTP diphosphatase	-
SP70585_RS03875 (SP70585_0787)	-	719759..720934 (-)	1176	WP_000680053.1	NAD(P)/FAD-dependent oxidoreductase	-
SP70585_RS03880 (SP70585_0788)	-	720993..721838 (-)	846	WP_000219939.1	DegV family protein	-
SP70585_RS03885 (SP70585_0789)	-	721963..722520 (+)	558	WP_000004139.1	TetR/AcrR family transcriptional regulator	-
SP70585_RS03890 (SP70585_0790)	-	722539..723006 (+)	468	WP_000136976.1	cytidine/deoxycytidylate deaminase family protein	-
SP70585_RS03895 (SP70585_0791)	upp	723095..723724 (+)	630	WP_001812010.1	uracil phosphoribosyltransferase	-
SP70585_RS03900 (SP70585_0792)	clpP	723899..724489 (+)	591	WP_000613481.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
SP70585_RS03905 (SP70585_0793)	-	724568..724816 (+)	249	WP_000462126.1	YlbG family protein	-
SP70585_RS03910 (SP70585_0794)	-	724917..726077 (+)	1161	WP_000726142.1	ABC transporter substrate-binding protein	-
SP70585_RS03915 (SP70585_0795)	-	726345..727214 (+)	870	WP_000941426.1	branched-chain amino acid ABC transporter permease	-
SP70585_RS03920 (SP70585_0796)	-	727218..728174 (+)	957	WP_000662292.1	branched-chain amino acid ABC transporter permease	-
SP70585_RS03925 (SP70585_0797)	-	728174..728938 (+)	765	WP_001186007.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21331.33 Da
• Isoelectric Point: 4.4910

>NTDB_id=33298 SP70585_RS03900 WP_000613481.1 723899..724489(+) (clpP) [Streptococcus pneumoniae 70585]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDSMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide

• Length: 591 bp

>NTDB_id=33298 SP70585_RS03900 WP_000613481.1 723899..724489(+) (clpP) [Streptococcus pneumoniae 70585]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAGTATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACGAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGGACTGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACTCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: C1C691

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	99.49	100	0.995
clpP	Streptococcus pneumoniae D39	99.49	100	0.995
clpP	Streptococcus pneumoniae R6	99.49	100	0.995
clpP	Streptococcus pneumoniae TIGR4	99.49	100	0.995
clpP	Streptococcus thermophilus LMG 18311	92.308	99.49	0.918
clpP	Streptococcus thermophilus LMD-9	92.308	99.49	0.918
clpP	Streptococcus pyogenes JRS4	90.256	99.49	0.898
clpP	Streptococcus pyogenes MGAS315	90.256	99.49	0.898
clpP	Streptococcus mutans UA159	85.641	99.49	0.852
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	85.128	99.49	0.847
clpP	Lactococcus lactis subsp. cremoris KW2	84.615	99.49	0.842
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571
clpP	Bacillus subtilis subsp. subtilis str. 168	58.333	97.959	0.571