Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SP70585_RS02880 Genome accession   NC_012468
Coordinates   535667..537343 (-) Length   558 a.a.
NCBI ID   WP_306293369.1    Uniprot ID   -
Organism   Streptococcus pneumoniae 70585     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 530667..542343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP70585_RS02850 (SP70585_0581) - 531002..531331 (-) 330 WP_000132572.1 hypothetical protein -
  SP70585_RS02855 (SP70585_0582) - 531607..531945 (+) 339 WP_000876676.1 LytTR family DNA-binding domain-containing protein -
  SP70585_RS02860 (SP70585_0583) comE/blpR 531950..532687 (+) 738 WP_001219147.1 response regulator transcription factor Regulator
  SP70585_RS02865 (SP70585_0584) - 532701..534041 (+) 1341 WP_001017622.1 sensor histidine kinase -
  SP70585_RS02870 (SP70585_0585) blpC 534083..534238 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  SP70585_RS02875 (SP70585_0586) - 534295..535656 (-) 1362 WP_001087624.1 bacteriocin secretion accessory protein -
  SP70585_RS02880 (SP70585_0587) comA/nlmT 535667..537343 (-) 1677 WP_306293369.1 peptide cleavage/export ABC transporter Regulator
  SP70585_RS14245 comA/nlmT 537237..537824 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  SP70585_RS02890 (SP70585_0589) blpI 538106..538303 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  SP70585_RS02895 (SP70585_0590) blpJ 538770..539039 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  SP70585_RS02900 (SP70585_0591) blpU 539108..539338 (+) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  SP70585_RS02905 (SP70585_0592) - 539341..539460 (+) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  SP70585_RS12200 (SP70585_0594) - 539757..539921 (+) 165 WP_000727118.1 hypothetical protein -
  SP70585_RS02920 (SP70585_0595) - 539918..540322 (+) 405 WP_000846944.1 hypothetical protein -
  SP70585_RS13100 - 540423..541237 (+) 815 Protein_564 IS5-like element IS1515 family transposase -
  SP70585_RS12205 - 541398..542204 (+) 807 Protein_565 IS5 family transposase -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62965.24 Da        Isoelectric Point: 6.7844

>NTDB_id=33295 SP70585_RS02880 WP_306293369.1 535667..537343(-) (comA/nlmT) [Streptococcus pneumoniae 70585]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=33295 SP70585_RS02880 WP_306293369.1 535667..537343(-) (comA/nlmT) [Streptococcus pneumoniae 70585]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTTTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGCCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.07

99.821

0.729
  comA Streptococcus mitis NCTC 12261

67.563

100

0.676
  comA Streptococcus pneumoniae D39

67.204

100

0.672
  comA Streptococcus pneumoniae R6

67.204

100

0.672
  comA Streptococcus pneumoniae Rx1

67.204

100

0.672
  comA Streptococcus mitis SK321

67.025

100

0.67
  comA Streptococcus gordonii str. Challis substr. CH1

66.905

100

0.67
  comA Streptococcus pneumoniae TIGR4

66.846

100

0.668

Multiple sequence alignment