Detailed information NTG0033146

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: SPJ_RS04480
• Genome accession: NC_012466
• Coordinates: 856567..857217 (+)
• Length: 216 a.a.
• NCBI ID: WP_000387333.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae JJA
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 851567..862217

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPJ_RS04440 (SPJ_0886)	-	852050..852265 (+)	216	WP_001232081.1	YozE family protein	-
SPJ_RS04445 (SPJ_0888)	-	852351..853319 (+)	969	WP_000658198.1	PhoH family protein	-
SPJ_RS04450 (SPJ_0889)	-	853512..854012 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
SPJ_RS04455 (SPJ_0890)	-	854015..854341 (+)	327	Protein_852	TfoX/Sxy family protein	-
SPJ_RS13305 (SPJ_0891)	ald	854642..855753 (-)	1112	Protein_853	alanine dehydrogenase	-
SPJ_RS04475 (SPJ_0894)	-	855930..856499 (+)	570	WP_000443744.1	GNAT family N-acetyltransferase	-
SPJ_RS04480 (SPJ_0895)	comEA/celA/cilE	856567..857217 (+)	651	WP_000387333.1	helix-hairpin-helix domain-containing protein	Machinery gene
SPJ_RS04485 (SPJ_0896)	comEC/celB	857201..859441 (+)	2241	WP_000942393.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SPJ_RS04490	-	859620..859808 (+)	189	WP_001808514.1	hypothetical protein	-
SPJ_RS04495 (SPJ_0897)	-	859841..860428 (+)	588	WP_000939895.1	ABC transporter ATP-binding protein	-
SPJ_RS04500 (SPJ_0898)	-	860432..861616 (+)	1185	WP_000655960.1	ABC transporter permease	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23191.51 Da
• Isoelectric Point: 5.5171

>NTDB_id=33146 SPJ_RS04480 WP_000387333.1 856567..857217(+) (comEA/celA/cilE) [Streptococcus pneumoniae JJA]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=33146 SPJ_RS04480 WP_000387333.1 856567..857217(+) (comEA/celA/cilE) [Streptococcus pneumoniae JJA]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTAAAGGAAACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATTGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	99.074	100	0.991
comEA/celA/cilE	Streptococcus pneumoniae D39	99.074	100	0.991
comEA/celA/cilE	Streptococcus pneumoniae R6	99.074	100	0.991
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	98.148	100	0.981
comEA/celA/cilE	Streptococcus mitis NCTC 12261	96.759	100	0.968
comEA/celA/cilE	Streptococcus mitis SK321	91.204	100	0.912
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Latilactobacillus sakei subsp. sakei 23K	33.906	100	0.366
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366