Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SPJ_RS02505 Genome accession   NC_012466
Coordinates   478455..480131 (-) Length   558 a.a.
NCBI ID   WP_196300924.1    Uniprot ID   -
Organism   Streptococcus pneumoniae JJA     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 473455..485131
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPJ_RS02475 (SPJ_0490) - 473788..474117 (-) 330 WP_000132572.1 hypothetical protein -
  SPJ_RS02480 (SPJ_0491) - 474393..474731 (+) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  SPJ_RS02485 (SPJ_0492) comE/blpR 474736..475473 (+) 738 WP_001219120.1 LytTR family DNA-binding domain-containing protein Regulator
  SPJ_RS02490 (SPJ_0493) - 475487..476827 (+) 1341 WP_001017642.1 sensor histidine kinase -
  SPJ_RS02495 (SPJ_0494) blpC 476898..477026 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  SPJ_RS02500 (SPJ_0495) - 477083..478444 (-) 1362 WP_001069060.1 bacteriocin secretion accessory protein -
  SPJ_RS02505 (SPJ_0496) comA/nlmT 478455..480131 (-) 1677 WP_196300924.1 peptide cleavage/export ABC transporter Regulator
  SPJ_RS13640 comA/nlmT 480025..480612 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  SPJ_RS02515 (SPJ_0498) blpM 480894..481148 (+) 255 WP_001093256.1 two-peptide bacteriocin subunit BlpM -
  SPJ_RS02520 (SPJ_0499) blpN 481164..481367 (+) 204 WP_001099490.1 two-peptide bacteriocin subunit BlpN -
  SPJ_RS02525 (SPJ_0500) cipB 481611..481760 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  SPJ_RS02530 (SPJ_0502) - 481864..481983 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  SPJ_RS11585 (SPJ_0503) - 482281..482445 (+) 165 WP_000727117.1 hypothetical protein -
  SPJ_RS11590 (SPJ_0504) - 482507..482845 (+) 339 WP_088804618.1 immunity protein -
  SPJ_RS02550 (SPJ_0506) - 483474..483857 (+) 384 WP_000877381.1 hypothetical protein -
  SPJ_RS02555 (SPJ_0507) - 483909..484598 (+) 690 WP_000760520.1 CPBP family intramembrane glutamic endopeptidase -
  SPJ_RS02560 (SPJ_0508) blpZ 484640..484888 (+) 249 WP_000276501.1 immunity protein BlpZ -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62949.24 Da        Isoelectric Point: 6.7844

>NTDB_id=33138 SPJ_RS02505 WP_196300924.1 478455..480131(-) (comA/nlmT) [Streptococcus pneumoniae JJA]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=33138 SPJ_RS02505 WP_196300924.1 478455..480131(-) (comA/nlmT) [Streptococcus pneumoniae JJA]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGATTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGACATATTTCTATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCACAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.07

99.821

0.729
  comA Streptococcus mitis NCTC 12261

67.563

100

0.676
  comA Streptococcus pneumoniae D39

67.204

100

0.672
  comA Streptococcus pneumoniae R6

67.204

100

0.672
  comA Streptococcus pneumoniae Rx1

67.204

100

0.672
  comA Streptococcus mitis SK321

67.025

100

0.67
  comA Streptococcus gordonii str. Challis substr. CH1

66.905

100

0.67
  comA Streptococcus pneumoniae TIGR4

66.846

100

0.668

Multiple sequence alignment