Detailed information    

insolico Bioinformatically predicted

Overview


Name   cipB   Type   Regulator
Locus tag   SPJ_RS02525 Genome accession   NC_012466
Coordinates   481611..481760 (+) Length   49 a.a.
NCBI ID   WP_001809846.1    Uniprot ID   Q00MV6
Organism   Streptococcus pneumoniae JJA     
Function   indirect induction of ComX; activation of comRS system (predicted from homology)   
Competence regulation

Genomic Context


Location: 476611..486760
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPJ_RS02495 (SPJ_0494) blpC 476898..477026 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  SPJ_RS02500 (SPJ_0495) - 477083..478444 (-) 1362 WP_001069060.1 bacteriocin secretion accessory protein -
  SPJ_RS02505 (SPJ_0496) comA/nlmT 478455..480131 (-) 1677 WP_196300924.1 peptide cleavage/export ABC transporter Regulator
  SPJ_RS13640 comA/nlmT 480025..480612 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  SPJ_RS02515 (SPJ_0498) blpM 480894..481148 (+) 255 WP_001093256.1 two-peptide bacteriocin subunit BlpM -
  SPJ_RS02520 (SPJ_0499) blpN 481164..481367 (+) 204 WP_001099490.1 two-peptide bacteriocin subunit BlpN -
  SPJ_RS02525 (SPJ_0500) cipB 481611..481760 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  SPJ_RS02530 (SPJ_0502) - 481864..481983 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  SPJ_RS11585 (SPJ_0503) - 482281..482445 (+) 165 WP_000727117.1 hypothetical protein -
  SPJ_RS11590 (SPJ_0504) - 482507..482845 (+) 339 WP_088804618.1 immunity protein -
  SPJ_RS02550 (SPJ_0506) - 483474..483857 (+) 384 WP_000877381.1 hypothetical protein -
  SPJ_RS02555 (SPJ_0507) - 483909..484598 (+) 690 WP_000760520.1 CPBP family intramembrane glutamic endopeptidase -
  SPJ_RS02560 (SPJ_0508) blpZ 484640..484888 (+) 249 WP_000276501.1 immunity protein BlpZ -
  SPJ_RS02565 (SPJ_0509) - 484918..485529 (+) 612 WP_000394043.1 type II CAAX endopeptidase family protein -
  SPJ_RS02570 (SPJ_0510) - 485690..486484 (+) 795 WP_000363002.1 phosphotransferase family protein -

Sequence


Protein


Download         Length: 49 a.a.        Molecular weight: 5149.92 Da        Isoelectric Point: 4.0439

>NTDB_id=33139 SPJ_RS02525 WP_001809846.1 481611..481760(+) (cipB) [Streptococcus pneumoniae JJA]
MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDGCATTV

Nucleotide


Download         Length: 150 bp        

>NTDB_id=33139 SPJ_RS02525 WP_001809846.1 481611..481760(+) (cipB) [Streptococcus pneumoniae JJA]
ATGAATACAAAAATGATGTCACAATTTTCTGTTATGGATAATGAAATGCTTGCTTGCGTTGAAGGTGGAGATATTGATTG
GGGAAGAAAAATTAGTTGTGCAGCAGGGGTTGCATATGGCGCAATTGATGGGTGTGCAACAACGGTTTGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q00MV6

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cipB Streptococcus mutans UA159

53.061

100

0.531


Multiple sequence alignment