Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   EJF26_RS03815 Genome accession   NZ_CP034442
Coordinates   738740..739387 (-) Length   215 a.a.
NCBI ID   WP_000452007.1    Uniprot ID   A0A3R9KBW6
Organism   Streptococcus oralis subsp. dentisani strain F0392     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 733740..744387
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJF26_RS03795 - 734336..735520 (-) 1185 WP_000652065.1 ABC transporter permease -
  EJF26_RS03800 - 735517..736110 (-) 594 WP_000956988.1 ATP-binding cassette domain-containing protein -
  EJF26_RS03810 comEC/celB 736516..738756 (-) 2241 WP_000942440.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  EJF26_RS03815 comEA/celA/cilE 738740..739387 (-) 648 WP_000452007.1 helix-hairpin-helix domain-containing protein Machinery gene
  EJF26_RS03820 - 739454..740023 (-) 570 WP_000443761.1 GNAT family N-acetyltransferase -
  EJF26_RS03830 ald 740200..741312 (+) 1113 WP_000904717.1 alanine dehydrogenase -
  EJF26_RS03835 - 741375..742361 (-) 987 WP_000658171.1 PhoH family protein -
  EJF26_RS03840 - 742442..742657 (-) 216 WP_001232085.1 YozE family protein -
  EJF26_RS03845 - 742654..743259 (-) 606 WP_029745494.1 GrpB family protein -
  EJF26_RS03850 cvfB 743271..744125 (-) 855 WP_001095460.1 RNA-binding virulence regulatory protein CvfB -

Sequence

Protein


Download         Length: 215 a.a.        Molecular weight: 23083.28 Da        Isoelectric Point: 5.9284

>NTDB_id=331344 EJF26_RS03815 WP_000452007.1 738740..739387(-) (comEA/celA/cilE) [Streptococcus oralis subsp. dentisani strain F0392]
MEVIIEKIKEYKIIVICAGLGLALGGFFLLKPSSQTSVKETNLPAEVAAVSKDSSSEKEVKKEEKEESPEQDLITVDVKG
AVKSPGIYDLPVGSRVHDAVQKAGGLTEEADSKSLNLAQKISDEALVYVPTKGEEASQQTASGTTPSTSKEKKVNLNKAS
LEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 648 bp        

>NTDB_id=331344 EJF26_RS03815 WP_000452007.1 738740..739387(-) (comEA/celA/cilE) [Streptococcus oralis subsp. dentisani strain F0392]
ATGGAAGTCATTATCGAGAAAATCAAAGAATATAAAATCATTGTCATCTGTGCAGGTTTGGGTTTGGCCTTAGGCGGTTT
TTTCCTGCTAAAGCCAAGTTCACAAACATCTGTGAAAGAAACAAATTTGCCGGCTGAAGTTGCAGCCGTTTCAAAGGATT
CATCGTCTGAAAAAGAAGTGAAGAAGGAAGAAAAGGAAGAATCTCCTGAACAAGATCTGATCACAGTAGATGTCAAAGGT
GCTGTTAAATCGCCGGGGATCTATGATTTGCCAGTAGGGAGTCGGGTCCATGATGCTGTTCAAAAGGCAGGTGGATTGAC
AGAGGAAGCAGATAGCAAGTCGCTCAATCTAGCTCAGAAAATCAGTGATGAGGCTCTGGTTTACGTTCCTACAAAGGGAG
AAGAAGCTAGTCAGCAGACTGCCTCTGGAACGACTCCTTCGACAAGTAAAGAAAAGAAGGTCAACCTAAACAAAGCTAGT
CTGGAAGAGCTCAAGCAGGTCAAAGGACTGGGAGGTAAACGAGCCCAGGATATTATCGACCATCGTGAGGCAAATGGTAA
GTTCAAGTCTGTAGACGAACTCAAGAAGGTCTCTGGTATTGGCGCAAAGACCATAGAAAAGTTAAAAGACTATGTTACAG
TGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-127)

Helix-hairpin-helix motif (HHH_3)

(150-213)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9KBW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

91.204

100

0.916
  comEA/celA/cilE Streptococcus mitis NCTC 12261

90.278

100

0.907
  comEA/celA/cilE Streptococcus pneumoniae Rx1

89.352

100

0.898
  comEA/celA/cilE Streptococcus pneumoniae D39

89.352

100

0.898
  comEA/celA/cilE Streptococcus pneumoniae R6

89.352

100

0.898
  comEA/celA/cilE Streptococcus mitis SK321

87.5

100

0.879
  comEA Lactococcus lactis subsp. cremoris KW2

40.529

100

0.428

Multiple sequence alignment