Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   EJF26_RS02275 Genome accession   NZ_CP034442
Coordinates   424304..425011 (+) Length   235 a.a.
NCBI ID   WP_000723164.1    Uniprot ID   A0A3R9KMG9
Organism   Streptococcus oralis subsp. dentisani strain F0392     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 419304..430011
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJF26_RS02250 - 419599..420270 (+) 672 WP_000151563.1 GTP pyrophosphokinase family protein -
  EJF26_RS02255 - 420254..421072 (+) 819 WP_000799044.1 NAD kinase -
  EJF26_RS02260 - 421069..421965 (+) 897 WP_001209998.1 RluA family pseudouridine synthase -
  EJF26_RS02265 pta 422008..422982 (+) 975 WP_000451594.1 phosphate acetyltransferase -
  EJF26_RS02270 mutY 423069..424247 (+) 1179 WP_000886162.1 A/G-specific adenine glycosylase -
  EJF26_RS02275 micA 424304..425011 (+) 708 WP_000723164.1 response regulator YycF Regulator
  EJF26_RS02280 micB 425004..426353 (+) 1350 WP_000568724.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EJF26_RS02285 vicX 426355..427164 (+) 810 WP_001289489.1 MBL fold metallo-hydrolase Regulator
  EJF26_RS02290 - 427196..427543 (-) 348 WP_001071322.1 thiol reductase thioredoxin -
  EJF26_RS02295 - 427654..429372 (-) 1719 WP_000222140.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27021.85 Da        Isoelectric Point: 4.6219

>NTDB_id=331335 EJF26_RS02275 WP_000723164.1 424304..425011(+) (micA) [Streptococcus oralis subsp. dentisani strain F0392]
MKKILVVDDEKPISDIIKFNMTKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLASVDSQETDEKKSQPLQIGDLEILPDAYVAKKYGEELEL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=331335 EJF26_RS02275 WP_000723164.1 424304..425011(+) (micA) [Streptococcus oralis subsp. dentisani strain F0392]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTCAATATGACCAAAGAAGGCTATGA
GGTTGTAACGGCCTTTAACGGTAGAGAAGCTATTGAGCTATTTGAGGCGGAGCAACCAGATATTATTATTCTAGACTTGA
TGCTACCTGAAATTGATGGTTTAGAAGTAGCCAAAGCCATTCGTAAGACGAGTAGTGTGCCTATCATTATGCTCTCAGCT
AAGGATAGTGAATTTGACAAGGTTATTGGTTTGGAGTTAGGTGCAGATGATTATGTCACAAAGCCTTTCTCAAACCGTGA
GTTGCAAGCTCGTGTGAAGGCTTTACTCCGTCGTACAGACCTCGCTTCAGTGGATAGTCAAGAAACTGATGAAAAGAAAT
CCCAACCCCTACAGATTGGCGATTTGGAAATTCTGCCAGACGCTTACGTAGCCAAAAAATATGGTGAGGAATTAGAGTTG
ACTCATCGTGAGTTTGAGCTCTTGTACCACTTGGCTTCCCATATTGGACAAGTCATTACTCGTGAACACTTACTTGAGAC
TGTTTGGGGCTATGATTATTTCGGTGATGTTCGTACAGTGGACGTGACCATCCGACGTTTGCGTGAAAAAATTGAAGACA
CTCCAAGCCGTCCAGAATACATCCTAACACGTCGTGGTGTGGGGTACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9KMG9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

91.453

99.574

0.911
  vicR Streptococcus mutans UA159

77.637

100

0.783
  covR Streptococcus salivarius strain HSISS4

43.162

99.574

0.43
  covR Lactococcus lactis subsp. lactis strain DGCC12653

42.424

98.298

0.417
  scnR Streptococcus mutans UA159

36.752

99.574

0.366

Multiple sequence alignment