Detailed information NTG0331336

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: EJF26_RS02280
• Genome accession: NZ_CP034442
• Coordinates: 425004..426353 (+)
• Length: 449 a.a.
• NCBI ID: WP_000568724.1
• Uniprot ID: A0A7T3DYU0
• Organism: Streptococcus oralis subsp. dentisani strain F0392
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 420004..431353

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EJF26_RS02255	-	420254..421072 (+)	819	WP_000799044.1	NAD kinase	-
EJF26_RS02260	-	421069..421965 (+)	897	WP_001209998.1	RluA family pseudouridine synthase	-
EJF26_RS02265	pta	422008..422982 (+)	975	WP_000451594.1	phosphate acetyltransferase	-
EJF26_RS02270	mutY	423069..424247 (+)	1179	WP_000886162.1	A/G-specific adenine glycosylase	-
EJF26_RS02275	micA	424304..425011 (+)	708	WP_000723164.1	response regulator YycF	Regulator
EJF26_RS02280	micB	425004..426353 (+)	1350	WP_000568724.1	cell wall metabolism sensor histidine kinase VicK	Regulator
EJF26_RS02285	vicX	426355..427164 (+)	810	WP_001289489.1	MBL fold metallo-hydrolase	Regulator
EJF26_RS02290	-	427196..427543 (-)	348	WP_001071322.1	thiol reductase thioredoxin	-
EJF26_RS02295	-	427654..429372 (-)	1719	WP_000222140.1	phospho-sugar mutase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51665.22 Da
• Isoelectric Point: 4.6821

>NTDB_id=331336 EJF26_RS02280 WP_000568724.1 425004..426353(+) (micB) [Streptococcus oralis subsp. dentisani strain F0392]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKQINQKIKDLIAGDYSRVLDMQGSSEITNITNNLNDLSE
VIRLTQENLEQETKRLNSILSYMTDGVLATNRRGQITMINDMAKKQLGIVKEEALNKSILELLKIEEEYELRDLITQIPE
LMIDSQNANGEYLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATTQLDVELINFTAFITFILNRFDKMRSQDEEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDEIED

Nucleotide

• Length: 1350 bp

>NTDB_id=331336 EJF26_RS02280 WP_000568724.1 425004..426353(+) (micB) [Streptococcus oralis subsp. dentisani strain F0392]
ATGATTGAAGATATTAGACAAACGATTCTGACCAGTGATTTTATCTTTATTTTGATTTTGCTGGGCTTTATCTTGGTGGT
CACCTTGCTATTGCTAGAAAATCGCCGTGATAATATTCGTCTAAAGCAGATTAATCAAAAAATTAAGGATTTGATTGCAG
GGGATTATTCTCGAGTATTAGATATGCAGGGAAGTTCTGAAATTACCAACATTACCAATAACCTCAATGATTTGTCTGAG
GTTATTCGTTTAACGCAGGAAAATCTGGAGCAAGAAACAAAAAGGCTTAACAGTATTCTTTCTTATATGACAGATGGAGT
TCTTGCAACCAATCGCCGTGGTCAGATTACTATGATTAACGATATGGCTAAGAAACAGCTGGGTATCGTAAAAGAAGAAG
CATTGAACAAAAGCATCCTAGAATTGCTTAAGATAGAGGAAGAGTATGAACTGCGTGACCTCATTACACAGATTCCCGAA
TTGATGATTGATTCCCAAAATGCTAATGGAGAATATCTTAGCCTTCGTGTGCGTTTTGCACTCATTCGTCGTGAGTCAGG
TTTCATCTCTGGTTTGGTTGCCGTTTTACATGATACGACCGAGCAGGAGAAGGAAGAACGCGAACGGAGACTCTTCGTTT
CAAACGTGAGTCATGAGTTGAGGACTCCTTTGACGAGTGTTAAATCTTATCTTGAAGCCTTAGACGAGGGAGCCTTATAT
GATCCTGTTGCTCCTGATTTTATCAAGGTTTCGCTTGATGAAACCAACCGTATGATGCGGATGGTGACAGATCTCTTGCA
TCTCTCTCGTATTGATAATGCGACCACTCAGTTGGATGTGGAATTGATTAATTTTACAGCCTTCATCACCTTTATCCTCA
ATCGTTTCGATAAGATGAGGAGCCAGGATGAAGAGAAAAAATATGAGCTGGTTAGAGATTACCCAATCAATTCAGTTTGG
ATCGAGATCGATACTGATAAGATGACCCAGGTGATTGATAATATTCTTAACAATGCTATCAAGTACTCACCAGATGGTGG
GAAAATTACTGTCAGCATGAAAACTACTGATGACCAGATGATTTTATCCATAAAAGACCAAGGTCTAGGTATTCCAAAGC
AAGATTTGCCGAAGATTTTCGACCGCTTCTACCGTGTGGATCGTGCAAGAAGTCGTGCTCAAGGTGGTACTGGTCTAGGT
TTGGCTATCGCCAAAGAAATCATCAAACAACACAATGGCTTTATTTGGGCCAAAAGTGAATACGGTAAGGGATCAACCTT
TACCATCGTGCTCCCTTATGATAAGGACGCAGTGAAAGAAGAAATATGGGAGGACGAAATAGAAGATTAG

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• PAS fold (PAS) (95-198)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

3D structure

• AlphaFold DB: A0A7T3DYU0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	89.522	97.773	0.875
vicK	Streptococcus mutans UA159	70.398	89.532	0.63