Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   SUB_RS09280 Genome accession   NC_012004
Coordinates   1850062..1851264 (+) Length   400 a.a.
NCBI ID   WP_015912153.1    Uniprot ID   A0A6L6G661
Organism   Streptococcus uberis 0140J     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1845062..1856264
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUB_RS09255 (SUB1866) - 1846291..1848861 (+) 2571 WP_015912151.1 YfhO family protein -
  SUB_RS09275 (SUB1867) rlmH 1849397..1849876 (-) 480 WP_015912152.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SUB_RS09280 (SUB1868) htrA 1850062..1851264 (+) 1203 WP_015912153.1 S1C family serine protease Regulator
  SUB_RS09285 (SUB1869) spo0J 1851342..1852118 (+) 777 WP_015912154.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42544.10 Da        Isoelectric Point: 5.1117

>NTDB_id=32950 SUB_RS09280 WP_015912153.1 1850062..1851264(+) (htrA) [Streptococcus uberis 0140J]
MPVSKFKHFFKYIMIVGLGFIGGALAFFVMNLLPHPSSTTNLNNPTTTSKVTYKNTTNTTKAVKVIQDAVVSVVNYQKND
SLNSAMDIFSQGDSSTKENDGLSIYSEGSGVIYKKDGDSAYLVTNNHVIDKAERIEIILADGSKVVGKLIGADTYSDLAV
VKISSDKIKTVAQFADSSKINIGEVAIAIGSPLGTEYANSVTEGIVSSLSRTVTLKNEEGQTVSTNAIQTDAAINPGNSG
GPLINIEGQIIGINSSKISQSKSSGNAVEGMGFAIPANDVIKIINQLESKGEVVRPALGISMVNLSDLSTNALDQLKVPK
NVTSGIVVAKVVDNMPASGKLEQYDIITEIDGEEVSSTSDLQSILYGHDINDTVKVTFYRGNDKKSTTIELTKTTKDLEK

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=32950 SUB_RS09280 WP_015912153.1 1850062..1851264(+) (htrA) [Streptococcus uberis 0140J]
ATGCCTGTGTCTAAGTTTAAACATTTTTTCAAATACATAATGATAGTCGGATTAGGCTTCATTGGTGGTGCTTTAGCATT
CTTTGTGATGAATCTGTTACCACATCCATCATCCACAACAAATCTTAATAACCCAACGACGACAAGTAAAGTAACCTATA
AAAATACTACTAATACGACTAAAGCTGTTAAAGTGATTCAAGATGCAGTTGTTTCTGTAGTTAACTATCAAAAAAATGAT
TCTTTAAACTCAGCCATGGATATTTTTAGTCAAGGTGATTCATCAACTAAAGAGAATGATGGACTTTCTATTTATAGTGA
AGGATCAGGTGTTATATACAAAAAAGATGGTGATTCTGCATATCTGGTAACCAACAACCACGTAATAGACAAAGCTGAAA
GAATTGAAATTATTTTAGCTGATGGTTCAAAAGTTGTTGGGAAATTAATTGGTGCTGACACTTATTCTGACCTGGCTGTT
GTAAAAATTTCTTCAGACAAAATTAAGACTGTAGCTCAGTTTGCAGATTCTTCCAAAATAAACATAGGTGAAGTTGCAAT
TGCAATTGGTAGTCCTCTTGGAACAGAATATGCTAATTCCGTAACTGAAGGAATTGTTTCAAGTTTAAGTAGAACAGTAA
CTTTAAAAAATGAAGAAGGACAAACTGTTTCAACTAATGCCATTCAAACAGATGCTGCTATTAACCCTGGAAACTCTGGC
GGACCTTTAATTAATATTGAAGGACAAATTATTGGAATAAACTCTAGCAAAATCTCACAGTCTAAATCATCTGGAAATGC
AGTCGAAGGAATGGGATTTGCAATTCCAGCTAATGACGTTATTAAAATTATTAACCAACTTGAAAGCAAAGGCGAAGTAG
TTCGACCTGCATTAGGTATTTCAATGGTTAATCTAAGTGATTTATCAACAAATGCCCTTGATCAGCTCAAAGTTCCAAAA
AATGTTACTAGTGGTATCGTAGTTGCTAAAGTCGTAGACAATATGCCTGCCTCAGGAAAACTTGAACAATATGATATTAT
CACTGAAATTGATGGGGAAGAAGTGAGCAGTACAAGTGATTTACAAAGTATTCTGTATGGGCATGATATTAATGATACCG
TAAAAGTCACTTTTTATAGAGGTAATGATAAGAAATCTACTACTATTGAATTAACTAAAACTACCAAAGATTTAGAAAAA
TAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(296-391)

Trypsin-like peptidase domain (Trypsin_2)

(108-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6L6G661

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

63.038

98.75

0.623
  htrA Streptococcus pneumoniae Rx1

56.091

98.5

0.552
  htrA Streptococcus pneumoniae D39

56.091

98.5

0.552
  htrA Streptococcus gordonii str. Challis substr. CH1

56.091

98.5

0.552
  htrA Streptococcus pneumoniae R6

56.091

98.5

0.552
  htrA Streptococcus pneumoniae TIGR4

56.091

98.5

0.552
  htrA Streptococcus mitis NCTC 12261

55.838

98.5

0.55

Multiple sequence alignment