Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   FNV65_RS08845 Genome accession   NZ_CP041612
Coordinates   1870900..1871502 (+) Length   200 a.a.
NCBI ID   WP_054233833.1    Uniprot ID   A0A1I2AVF0
Organism   Streptomyces sp. S1A1-8     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 1865900..1876502
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNV65_RS08825 (FNV65_08950) - 1866803..1867812 (-) 1010 Protein_1816 IS110 family transposase -
  FNV65_RS08830 (FNV65_08955) - 1868178..1868660 (-) 483 WP_143600466.1 VOC family protein -
  FNV65_RS08835 (FNV65_08960) - 1868819..1870042 (+) 1224 WP_143612575.1 epoxide hydrolase family protein -
  FNV65_RS08840 (FNV65_08965) clpP 1870245..1870898 (+) 654 WP_054233834.1 ATP-dependent Clp protease proteolytic subunit Regulator
  FNV65_RS08845 (FNV65_08970) clpP 1870900..1871502 (+) 603 WP_054233833.1 ATP-dependent Clp protease proteolytic subunit Regulator
  FNV65_RS56710 (FNV65_08975) - 1871572..1872045 (-) 474 WP_097283232.1 helix-turn-helix transcriptional regulator -
  FNV65_RS08855 (FNV65_08980) - 1872133..1872654 (-) 522 WP_079089687.1 DinB family protein -
  FNV65_RS08860 (FNV65_08985) - 1872929..1873156 (+) 228 WP_054233831.1 DUF5133 domain-containing protein -
  FNV65_RS08865 (FNV65_08990) - 1873266..1874609 (-) 1344 WP_164331635.1 diacylglycerol kinase family protein -
  FNV65_RS08870 (FNV65_08995) - 1874823..1875266 (-) 444 WP_054233829.1 response regulator -

Sequence

Protein


Download         Length: 200 a.a.        Molecular weight: 21700.64 Da        Isoelectric Point: 5.0288

>NTDB_id=327272 FNV65_RS08845 WP_054233833.1 1870900..1871502(+) (clpP) [Streptomyces sp. S1A1-8]
MGTYTIPNVVERTPQGERSYDVFSRLLSERIIFLGTEIDDGVANVVIAQLLHLESSNPESEIAIYINSPGGSFTSLMAIY
DTMTFVQAPISTFCVGQAASTAAVLLAGGDPGRRFVLEHARVLLGQPASGGRQGTVSDLALQAKEMLRIRAQVEEVLSRH
THHDVPTLRADMDRDKVFTAQEAVAYGLADEVLSRRLATV

Nucleotide


Download         Length: 603 bp        

>NTDB_id=327272 FNV65_RS08845 WP_054233833.1 1870900..1871502(+) (clpP) [Streptomyces sp. S1A1-8]
GTGGGTACGTACACGATTCCGAACGTCGTCGAGCGGACCCCGCAGGGCGAGCGGTCCTACGACGTCTTCAGCCGGCTGCT
GTCCGAGCGGATCATCTTTCTCGGCACCGAGATCGACGACGGGGTCGCCAACGTCGTCATCGCGCAACTCCTCCATCTGG
AGTCGTCGAACCCGGAGAGCGAGATCGCGATCTACATCAACTCGCCCGGTGGGTCGTTCACTTCGCTCATGGCGATCTAC
GACACGATGACGTTCGTACAGGCGCCGATCTCGACGTTCTGCGTCGGCCAGGCGGCCTCCACGGCGGCGGTACTGCTGGC
CGGCGGCGATCCCGGACGGCGGTTCGTGCTGGAGCACGCGCGCGTGCTGCTCGGCCAGCCCGCGAGCGGCGGCCGGCAGG
GGACGGTGTCCGACCTCGCCCTCCAGGCCAAGGAGATGCTCCGTATCCGCGCCCAGGTCGAGGAGGTCCTCTCCCGGCAC
ACGCACCACGACGTGCCGACCCTGCGCGCGGACATGGACCGCGACAAGGTGTTCACCGCGCAGGAGGCCGTGGCGTACGG
ACTCGCGGACGAGGTCCTGAGCCGACGGCTCGCGACGGTCTGA

Domains

Predicted by InterProScan.

Clp protease (CLP_protease)

(15-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I2AVF0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

48.148

94.5

0.455
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

46.316

95

0.44
  clpP Streptococcus mutans UA159

40.212

94.5

0.38
  clpP Streptococcus pneumoniae R6

39.583

96

0.38
  clpP Streptococcus pneumoniae TIGR4

39.583

96

0.38
  clpP Streptococcus pneumoniae Rx1

39.583

96

0.38
  clpP Streptococcus pneumoniae D39

39.583

96

0.38
  clpP Streptococcus pyogenes JRS4

39.683

94.5

0.375
  clpP Streptococcus pyogenes MGAS315

39.683

94.5

0.375
  clpP Lactococcus lactis subsp. cremoris KW2

38.743

95.5

0.37
  clpP Streptococcus thermophilus LMG 18311

38.021

96

0.365
  clpP Streptococcus thermophilus LMD-9

38.021

96

0.365

Multiple sequence alignment