Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SPN23F_RS04480 Genome accession   NC_011900
Coordinates   853828..854478 (+) Length   216 a.a.
NCBI ID   WP_000387328.1    Uniprot ID   A0A4N9N7Z7
Organism   Streptococcus pneumoniae ATCC 700669     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 848828..859478
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN23F_RS04440 (SPN23F08690) - 849311..849526 (+) 216 WP_001232085.1 YozE family protein -
  SPN23F_RS04445 (SPN23F08700) - 849612..850580 (+) 969 WP_000658183.1 PhoH family protein -
  SPN23F_RS12185 - 850558..850737 (-) 180 WP_001813350.1 hypothetical protein -
  SPN23F_RS04450 (SPN23F08720) - 850773..851274 (+) 502 Protein_851 GNAT family N-acetyltransferase -
  SPN23F_RS04455 (SPN23F08740) - 851277..851603 (+) 327 Protein_852 TfoX/Sxy family protein -
  SPN23F_RS13855 (SPN23F08750) ald 851904..853014 (-) 1111 Protein_853 alanine dehydrogenase -
  SPN23F_RS04475 (SPN23F08780) - 853191..853760 (+) 570 WP_000443777.1 GNAT family N-acetyltransferase -
  SPN23F_RS04480 (SPN23F08790) comEA/celA/cilE 853828..854478 (+) 651 WP_000387328.1 ComEA family DNA-binding protein Machinery gene
  SPN23F_RS04485 (SPN23F08800) comEC/celB 854462..856702 (+) 2241 WP_000942392.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SPN23F_RS13860 - 856844..857068 (+) 225 WP_000583432.1 hypothetical protein -
  SPN23F_RS04495 (SPN23F08820) - 857101..857688 (+) 588 WP_000939884.1 ATP-binding cassette domain-containing protein -
  SPN23F_RS04500 (SPN23F08830) - 857692..858873 (+) 1182 WP_000655951.1 membrane protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23230.59 Da        Isoelectric Point: 5.0667

>NTDB_id=32675 SPN23F_RS04480 WP_000387328.1 853828..854478(+) (comEA/celA/cilE) [Streptococcus pneumoniae ATCC 700669]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEEEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=32675 SPN23F_RS04480 WP_000387328.1 853828..854478(+) (comEA/celA/cilE) [Streptococcus pneumoniae ATCC 700669]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAGAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4N9N7Z7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

99.537

100

0.995
  comEA/celA/cilE Streptococcus pneumoniae D39

99.537

100

0.995
  comEA/celA/cilE Streptococcus pneumoniae R6

99.537

100

0.995
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

96.759

100

0.968
  comEA/celA/cilE Streptococcus mitis NCTC 12261

95.833

100

0.958
  comEA/celA/cilE Streptococcus mitis SK321

89.815

100

0.898
  comEA Lactococcus lactis subsp. cremoris KW2

43.172

100

0.454
  comEA Bacillus subtilis subsp. subtilis str. 168

41.579

87.963

0.366

Multiple sequence alignment