Detailed information NTG0326058

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EGX80_RS07170
• Genome accession: NZ_CP033815
• Coordinates: 1339539..1340540 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain FDAARGOS_514
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1334539..1345540

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX80_RS07145 (EGX80_07155)	-	1335213..1335896 (-)	684	WP_011017476.1	DUF969 domain-containing protein	-
EGX80_RS07150 (EGX80_07160)	-	1336107..1337033 (-)	927	WP_011106859.1	glycosyltransferase family 2 protein	-
EGX80_RS07155 (EGX80_07165)	-	1337178..1337555 (-)	378	WP_002985686.1	VOC family protein	-
EGX80_RS07160 (EGX80_07170)	-	1337566..1338231 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
EGX80_RS07165 (EGX80_07175)	-	1338280..1339365 (-)	1086	WP_011054264.1	Xaa-Pro peptidase family protein	-
EGX80_RS07170 (EGX80_07180)	ccpA	1339539..1340540 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
EGX80_RS07175 (EGX80_07185)	-	1340671..1341669 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
EGX80_RS07180 (EGX80_07190)	-	1341671..1343005 (+)	1335	WP_002985676.1	glycosyltransferase family 4 protein	-
EGX80_RS07185 (EGX80_07195)	thrS	1343427..1345370 (+)	1944	WP_011054265.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=326058 EGX80_RS07170 WP_002985680.1 1339539..1340540(+) (ccpA) [Streptococcus pyogenes strain FDAARGOS_514]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=326058 EGX80_RS07170 WP_002985680.1 1339539..1340540(+) (ccpA) [Streptococcus pyogenes strain FDAARGOS_514]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCACGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559