Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   SMUNN2025_RS06200 Genome accession   NC_013928
Coordinates   1269172..1271163 (-) Length   663 a.a.
NCBI ID   WP_002264166.1    Uniprot ID   -
Organism   Streptococcus mutans NN2025     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1264172..1276163
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNN2025_RS06175 (SmuNN2025_1198) - 1264526..1265662 (-) 1137 WP_012997842.1 aminotransferase -
  SMUNN2025_RS06180 (SmuNN2025_1199) - 1265878..1266693 (-) 816 WP_002265552.1 transporter substrate-binding domain-containing protein -
  SMUNN2025_RS06185 (SmuNN2025_1200) - 1266801..1267265 (-) 465 WP_041160320.1 8-oxo-dGTP diphosphatase -
  SMUNN2025_RS06190 (SmuNN2025_1201) - 1267323..1268213 (-) 891 WP_019312773.1 helix-turn-helix transcriptional regulator -
  SMUNN2025_RS10750 - 1268404..1268517 (-) 114 WP_002264165.1 hypothetical protein -
  SMUNN2025_RS10100 - 1268517..1268843 (-) 327 WP_162465515.1 hypothetical protein -
  SMUNN2025_RS10465 - 1268849..1268989 (-) 141 WP_002303124.1 hypothetical protein -
  SMUNN2025_RS06200 (SmuNN2025_1202) uvrB 1269172..1271163 (-) 1992 WP_002264166.1 excinuclease ABC subunit UvrB Machinery gene
  SMUNN2025_RS06205 (SmuNN2025_1203) - 1271372..1272289 (-) 918 WP_002265557.1 CPBP family intramembrane glutamic endopeptidase -
  SMUNN2025_RS06210 (SmuNN2025_1204) - 1272484..1274670 (+) 2187 WP_012997844.1 ABC transporter substrate-binding protein/permease -
  SMUNN2025_RS06215 (SmuNN2025_1205) - 1274670..1275410 (+) 741 WP_002264169.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 76024.91 Da        Isoelectric Point: 4.5849

>NTDB_id=32427 SMUNN2025_RS06200 WP_002264166.1 1269172..1271163(-) (uvrB) [Streptococcus mutans NN2025]
MIDRKDNNQFHLVSKYEPSGDQPEAIEALVDNIEGGEKAQILKGATGTGKTYTMSQVIQKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPSQEISRDQLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREIESLTGRVL
GEVDHLAIFPATHFMTNDEHMEVAIAKIQKEMEEQVRLFEAEGKLIEAQRIRQRTEYDVEMLREMGYTSGVENYSRHMDG
RSEGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEMEQTDTVIEQIIRPTGLLDPEVEVRPTMGQMDDLLGEINSRADKGERIFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSQGHVIMYADT
VTQSMRRAIDETHRRRQIQMAYNEEHGIIPQTIKKDIRDLIAITKANDSEVAEEAVDYNAMTKSERQEAIKKLQKQMQEA
AELLDFELAAQIRDMVLELKAMD

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=32427 SMUNN2025_RS06200 WP_002264166.1 1269172..1271163(-) (uvrB) [Streptococcus mutans NN2025]
ATGATAGATAGGAAAGATAATAACCAGTTTCATCTGGTTTCAAAATATGAGCCGTCTGGTGATCAGCCCGAGGCCATTGA
GGCTTTGGTTGACAATATTGAAGGTGGTGAGAAAGCGCAAATTCTCAAAGGGGCGACTGGAACGGGGAAAACCTATACCA
TGAGCCAAGTTATTCAAAAGGTCAATAAACCAACTTTAGTCATCGCTCATAATAAAACTCTAGCTGGTCAGCTTTACGGT
GAATTTAAAGAATTTTTCCCAGATAATGCAGTTGAGTATTTTGTTTCTTACTATGATTATTATCAGCCTGAAGCCTATGT
GCCATCAAGTGATACCTATATTGAAAAGGATAGTTCAGTTAATGATGAGATTGATAAGCTCCGACATTCGGCAACATCTG
CCCTTTTGGAACGCAATGATGTCATTGTCGTAGCATCCGTCTCCTGTATTTATGGTTTAGGGTCACCCAAGGAATATGCA
GATAGCGTGGTTAGTCTGCGGCCCAGTCAGGAGATTTCTCGCGACCAACTGTTAAATGATTTGGTAGATATTCAGTTTGA
GCGCAACGATATTGATTTCCAGCGGGGACGTTTTCGTGTGCGCGGCGATGTGGTGGAAATTTTTCCAGCATCACGTGATG
AACATGCTTTTCGTGTGGAATTTTTCGGTGATGAGATTGATCGTATCAGAGAAATTGAGAGTTTAACAGGTCGTGTTCTT
GGTGAAGTAGATCACTTGGCTATTTTTCCAGCAACTCACTTTATGACTAACGATGAGCACATGGAAGTGGCTATTGCCAA
GATTCAAAAAGAAATGGAAGAGCAAGTCAGGCTTTTTGAAGCAGAAGGGAAATTGATTGAAGCACAGCGCATTCGCCAAA
GAACAGAGTATGATGTGGAAATGCTGCGGGAGATGGGCTATACTAGCGGCGTTGAAAACTATTCGCGTCATATGGATGGC
CGCAGTGAGGGAGAACCGCCTTATACACTTCTTGACTTTTTTCCAGAGGATTTCCTCATCATGATCGATGAAAGTCACAT
GACTATGGGGCAGATTAAAGGTATGTATAATGGTGACCGATCGCGCAAGGAGATGTTGGTCAACTATGGTTTTCGTCTGC
CAAGTGCGCTGGATAATCGACCGCTGCGTCGAGAAGAATTTGAAAGCCATGTCCATCAGATTGTCTATGTTTCAGCAACA
CCAGGTGACTATGAGATGGAGCAGACGGACACGGTTATTGAACAAATTATCCGTCCGACTGGTCTCTTGGATCCAGAAGT
GGAAGTTCGGCCAACCATGGGACAGATGGATGATCTGCTGGGTGAAATCAATAGCAGAGCTGATAAAGGCGAGCGGATCT
TTATTACAACCTTAACCAAGAAAATGGCGGAAGATTTGACTGACTACCTCAAGGAAATGGGGGTCAAGGTCAAGTACATG
CATTCTGACATCAAGACTCTGGAACGTACTGAAATTATCCGCGACCTTCGTTTAGGTGTTTTTGATGTTCTTATCGGTAT
CAATTTGCTGCGCGAAGGTATTGATGTGCCAGAGGTTAGTCTGGTTGCCATTCTTGATGCAGACAAAGAAGGTTTTCTCC
GCAATGAACGTGGTCTTATCCAGACCATTGGACGGGCTGCGCGCAACAGTCAAGGACATGTTATTATGTATGCTGATACT
GTGACACAATCCATGCGTCGCGCTATTGATGAGACCCACCGCCGCCGCCAAATCCAAATGGCTTACAATGAAGAGCATGG
TATTATTCCACAAACCATCAAAAAAGATATCCGTGATCTTATCGCGATTACAAAAGCAAATGACTCTGAAGTGGCTGAGG
AGGCTGTGGATTATAATGCAATGACCAAATCTGAACGCCAAGAAGCCATCAAGAAACTGCAAAAACAAATGCAAGAAGCA
GCTGAACTGCTGGACTTCGAATTGGCTGCCCAAATCCGCGACATGGTCTTAGAATTGAAGGCGATGGATTAG

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(164-254)

UvrB/uvrC motif (UVR)

(628-661)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

Helicase conserved C-terminal domain (Helicase_C)

(445-549)

Ultra-violet resistance protein B (UvrB)

(556-598)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

89.291

100

0.893
  uvrB Streptococcus pneumoniae D39

89.291

100

0.893
  uvrB Streptococcus pneumoniae TIGR4

89.14

100

0.891

Multiple sequence alignment