Detailed information NTG0323121

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: EB816_RS01875
• Genome accession: NZ_CP033337
• Coordinates: 344721..345311 (+)
• Length: 196 a.a.
• NCBI ID: WP_002985850.1
• Uniprot ID: A0A9X8T4H8
• Organism: Streptococcus pyogenes strain TSPY453
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 339721..350311

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EB816_RS01855 (EB816_01860)	-	340534..341979 (-)	1446	WP_023612140.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
EB816_RS01860 (EB816_01865)	-	342067..343701 (+)	1635	WP_023612124.1	polysaccharide biosynthesis protein	-
EB816_RS01865 (EB816_01870)	upp	343869..344498 (+)	630	WP_023612134.1	uracil phosphoribosyltransferase	-
EB816_RS01875 (EB816_01880)	clpP	344721..345311 (+)	591	WP_002985850.1	ATP-dependent Clp protease proteolytic subunit	Regulator
EB816_RS01885 (EB816_01890)	-	345803..346078 (+)	276	WP_002985847.1	YlbG family protein	-
EB816_RS01890 (EB816_01895)	tmk	346327..346962 (+)	636	WP_002990917.1	dTMP kinase	-
EB816_RS01895 (EB816_01900)	-	346980..347855 (+)	876	WP_002985844.1	DNA polymerase III subunit delta'	-
EB816_RS10300	-	347980..348114 (+)	135	WP_014635307.1	tpl protein	-
EB816_RS01905 (EB816_01910)	yabA	348518..348841 (+)	324	WP_002985838.1	DNA replication initiation control protein YabA	-
EB816_RS01910 (EB816_01915)	rsmI	348846..349709 (+)	864	WP_021733048.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
EB816_RS01915 (EB816_01920)	-	349736..350128 (+)	393	WP_002985833.1	DUF5684 domain-containing protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21648.88 Da
• Isoelectric Point: 5.2834

>NTDB_id=323121 EB816_RS01875 WP_002985850.1 344721..345311(+) (clpP) [Streptococcus pyogenes strain TSPY453]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=323121 EB816_RS01875 WP_002985850.1 344721..345311(+) (clpP) [Streptococcus pyogenes strain TSPY453]
ATGATTCCTGTTGTTATTGAACAAACTAGTCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTGAAAGACCGTAT
TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA
ACACGAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC
TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA
AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGCACAGGCGGTGGCACGCAACAAA
CGGATATGGCTATCGCAGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCGCAAAATGCTGGAAAA
ACGATTAAACAAATCCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA
TGAAATCATGGAAAACAACGAACTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes MGAS315	100	100	1
clpP	Streptococcus pyogenes JRS4	100	100	1
clpP	Streptococcus mutans UA159	90.816	100	0.908
clpP	Streptococcus pneumoniae Rx1	90.769	99.49	0.903
clpP	Streptococcus pneumoniae D39	90.769	99.49	0.903
clpP	Streptococcus pneumoniae R6	90.769	99.49	0.903
clpP	Streptococcus pneumoniae TIGR4	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.224	100	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	85.714	100	0.857
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561