Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   EB818_RS06015 Genome accession   NZ_CP033335
Coordinates   1174053..1174235 (-) Length   60 a.a.
NCBI ID   WP_129322727.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY208     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1174053..1187266 1174053..1174235 within 0


Gene organization within MGE regions


Location: 1174053..1187266
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EB818_RS06015 (EB818_06025) prx 1174053..1174235 (-) 183 WP_129322727.1 Paratox Regulator
  EB818_RS06020 (EB818_06030) mf2 1174475..1175233 (+) 759 WP_011184727.1 DNase Mf2 -
  EB818_RS06025 (EB818_06035) speC 1175344..1176051 (+) 708 WP_002985327.1 streptococcal pyrogenic exotoxin SpeC -
  EB818_RS06030 (EB818_06040) - 1176127..1176315 (-) 189 WP_129322728.1 hypothetical protein -
  EB818_RS06035 (EB818_06045) - 1176318..1176746 (-) 429 WP_115219682.1 DUF1617 family protein -
  EB818_RS06040 (EB818_06050) - 1176758..1178644 (-) 1887 WP_129322729.1 gp58-like family protein -
  EB818_RS06045 (EB818_06055) - 1178655..1178969 (-) 315 WP_021340983.1 hypothetical protein -
  EB818_RS06050 (EB818_06060) - 1178971..1179699 (-) 729 WP_129322730.1 hypothetical protein -
  EB818_RS06055 (EB818_06065) - 1179696..1179971 (-) 276 WP_011054885.1 VRR-NUC domain-containing protein -
  EB818_RS06060 (EB818_06070) - 1180357..1182654 (-) 2298 Protein_1121 phage/plasmid primase, P4 family -
  EB818_RS06065 (EB818_06075) - 1182794..1183054 (+) 261 WP_023611024.1 hypothetical protein -
  EB818_RS06070 (EB818_06080) - 1183153..1183890 (-) 738 WP_023611022.1 phage antirepressor KilAC domain-containing protein -
  EB818_RS06075 (EB818_06085) - 1183902..1184093 (-) 192 WP_002993390.1 hypothetical protein -
  EB818_RS06080 (EB818_06090) - 1184729..1184824 (+) 96 WP_020837421.1 type I toxin-antitoxin system Fst family toxin -
  EB818_RS06085 (EB818_06095) - 1185247..1185594 (+) 348 WP_002994741.1 helix-turn-helix transcriptional regulator -
  EB818_RS06090 (EB818_06100) - 1185598..1185978 (+) 381 WP_129322731.1 ImmA/IrrE family metallo-endopeptidase -
  EB818_RS06095 (EB818_06105) - 1185990..1186151 (+) 162 Protein_1128 DUF4177 domain-containing protein -
  EB818_RS06100 (EB818_06110) - 1186148..1186912 (+) 765 Protein_1129 site-specific integrase -
  EB818_RS06105 (EB818_06115) - 1186991..1187266 (-) 276 WP_002983920.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 60 a.a.        Molecular weight: 6959.93 Da        Isoelectric Point: 4.1954

>NTDB_id=323027 EB818_RS06015 WP_129322727.1 1174053..1174235(-) (prx) [Streptococcus pyogenes strain TSPY208]
MLTYDEFKQAIDNGYITGDTVIIVRKNGQIFDYVLPGEKVRPWEVVTDEKVEEVLVELSR

Nucleotide


Download         Length: 183 bp        

>NTDB_id=323027 EB818_RS06015 WP_129322727.1 1174053..1174235(-) (prx) [Streptococcus pyogenes strain TSPY208]
ATGCTAACATACGACGAATTTAAGCAAGCAATTGACAACGGATATATCACAGGAGACACAGTAATAATCGTGCGCAAAAA
CGGACAGATTTTTGATTATGTGTTGCCTGGTGAGAAAGTCAGACCATGGGAGGTTGTGACAGACGAAAAAGTGGAAGAGG
TGCTAGTGGAGCTTTCGAGATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS8232

86.667

100

0.867
  prx Streptococcus pyogenes MGAS315

85

100

0.85
  prx Streptococcus pyogenes MGAS315

80

100

0.8
  prx Streptococcus pyogenes MGAS315

75

100

0.75
  prx Streptococcus pyogenes MGAS315

95.238

70

0.667
  prx Streptococcus pyogenes MGAS315

85.366

68.333

0.583
  prx Streptococcus pyogenes MGAS315

80.488

68.333

0.55

Multiple sequence alignment