Detailed information NTG0320874

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: D9779_RS13550
• Genome accession: NZ_CP033052
• Coordinates: 2608872..2609489 (-)
• Length: 205 a.a.
• NCBI ID: WP_121642936.1
• Uniprot ID: -
• Organism: Bacillus vallismortis strain Bac111
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2603872..2614489

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D9779_RS13520	rpsT	2604174..2604440 (+)	267	WP_010330723.1	30S ribosomal protein S20	-
D9779_RS13525	holA	2604455..2605498 (-)	1044	WP_010330724.1	DNA polymerase III subunit delta	-
D9779_RS13530	-	2605538..2605687 (-)	150	WP_121642933.1	hypothetical protein	-
D9779_RS13535	-	2605728..2605862 (+)	135	WP_003229983.1	YqzM family protein	-
D9779_RS13540	-	2605903..2608232 (-)	2330	Protein_2595	DNA internalization-related competence protein ComEC/Rec2	-
D9779_RS13545	-	2608236..2608805 (-)	570	WP_121642935.1	ComE operon protein 2	-
D9779_RS13550	comEA	2608872..2609489 (-)	618	WP_121642936.1	helix-hairpin-helix domain-containing protein	Machinery gene
D9779_RS13555	comER	2609573..2610394 (+)	822	WP_010330728.1	late competence protein ComER	-
D9779_RS13560	-	2610460..2611203 (-)	744	WP_010330729.1	class I SAM-dependent DNA methyltransferase	-
D9779_RS13565	rsfS	2611200..2611556 (-)	357	WP_039074535.1	ribosome silencing factor	-
D9779_RS13570	yqeK	2611574..2612134 (-)	561	WP_121642937.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
D9779_RS13575	-	2612124..2612693 (-)	570	WP_010330732.1	nicotinate-nucleotide adenylyltransferase	-
D9779_RS13580	yhbY	2612705..2612995 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-
D9779_RS13585	aroE	2612989..2613831 (-)	843	WP_121642938.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 205 a.a.
• Molecular weight: 22116.83 Da
• Isoelectric Point: 4.4900

>NTDB_id=320874 D9779_RS13550 WP_121642936.1 2608872..2609489(-) (comEA) [Bacillus vallismortis strain Bac111]
MNWLIQHKKAIILAAFAAAFIAVIFFLASRENKEPVKQAVSTETENPEVKQEAVKDDSDDTIVIDIKGAVQHPGVYEMQT
GDRVSQAIERAGGASEQADEMQVNLAELLQDGTVVYIPKKGEEESGRQGSGDDVRSGGGKEALVNINTATLEELQGIPGV
GPSKAEAIIAYREENGRFQTIEEITKVSGIGEKSFDKIKSSITVK

Nucleotide

• Length: 618 bp

>NTDB_id=320874 D9779_RS13550 WP_121642936.1 2608872..2609489(-) (comEA) [Bacillus vallismortis strain Bac111]
ATGAATTGGTTGATCCAGCATAAAAAAGCAATCATTTTAGCGGCTTTTGCGGCTGCTTTCATAGCGGTTATTTTCTTCTT
GGCCAGCAGGGAAAACAAAGAGCCGGTAAAGCAGGCTGTATCAACTGAGACAGAAAATCCGGAGGTAAAGCAGGAGGCCG
TAAAAGACGATTCAGACGATACCATTGTGATTGATATAAAAGGGGCTGTCCAGCATCCCGGCGTTTATGAGATGCAAACA
GGGGACCGAGTATCTCAGGCAATTGAGAGAGCGGGCGGGGCCAGTGAACAAGCAGATGAGATGCAAGTTAACTTGGCGGA
GTTGCTGCAGGACGGGACAGTGGTGTATATTCCGAAAAAGGGAGAGGAGGAATCGGGGCGGCAAGGGTCCGGAGACGATG
TGAGAAGCGGCGGCGGGAAAGAAGCACTGGTAAATATCAATACAGCAACCTTAGAGGAATTACAAGGCATCCCAGGGGTG
GGACCATCAAAAGCTGAAGCTATTATCGCATACCGTGAAGAAAACGGGCGTTTCCAGACAATTGAAGAGATCACGAAGGT
GTCGGGAATCGGTGAGAAGTCGTTTGATAAAATAAAGTCTTCCATTACAGTAAAGTGA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (141-203)

• SLBB domain (SLBB) (63-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	82.439	100	0.824
comEA	Staphylococcus aureus MW2	38.249	100	0.405
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	38.095	100	0.39
comEA	Staphylococcus aureus N315	36.866	100	0.39
comEA/celA/cilE	Streptococcus pneumoniae D39	38.049	100	0.38
comEA/celA/cilE	Streptococcus pneumoniae Rx1	38.049	100	0.38
comEA/celA/cilE	Streptococcus pneumoniae R6	38.049	100	0.38