Detailed information NTG0318336

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: D8S77_RS07620
• Genome accession: NZ_CP032700
• Coordinates: 1494543..1495133 (-)
• Length: 196 a.a.
• NCBI ID: WP_002985850.1
• Uniprot ID: A0A9X8T4H8
• Organism: Streptococcus pyogenes strain TSPY556
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1489543..1500133

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D8S77_RS07585 (D8S77_07590)	-	1489726..1490118 (-)	393	WP_002985833.1	DUF5684 domain-containing protein	-
D8S77_RS07590 (D8S77_07595)	rsmI	1490145..1491008 (-)	864	WP_129322198.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
D8S77_RS07595 (D8S77_07600)	yabA	1491013..1491336 (-)	324	WP_002985838.1	DNA replication initiation control protein YabA	-
D8S77_RS09480	-	1491741..1491875 (-)	135	WP_014635307.1	tpl protein	-
D8S77_RS07605 (D8S77_07610)	-	1492000..1492875 (-)	876	WP_129322200.1	DNA polymerase III subunit delta'	-
D8S77_RS07610 (D8S77_07615)	tmk	1492893..1493528 (-)	636	WP_010921930.1	dTMP kinase	-
D8S77_RS07615 (D8S77_07620)	-	1493777..1494052 (-)	276	WP_002985847.1	YlbG family protein	-
D8S77_RS07620 (D8S77_07625)	clpP	1494543..1495133 (-)	591	WP_002985850.1	ATP-dependent Clp protease proteolytic subunit	Regulator
D8S77_RS07630 (D8S77_07635)	upp	1495357..1495986 (-)	630	WP_002985854.1	uracil phosphoribosyltransferase	-
D8S77_RS07635 (D8S77_07640)	-	1496154..1497788 (-)	1635	WP_111712503.1	putative polysaccharide biosynthesis protein	-
D8S77_RS07640 (D8S77_07645)	-	1497876..1499321 (+)	1446	WP_129322202.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21648.88 Da
• Isoelectric Point: 5.2834

>NTDB_id=318336 D8S77_RS07620 WP_002985850.1 1494543..1495133(-) (clpP) [Streptococcus pyogenes strain TSPY556]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=318336 D8S77_RS07620 WP_002985850.1 1494543..1495133(-) (clpP) [Streptococcus pyogenes strain TSPY556]
ATGATTCCTGTTGTTATTGAACAAACTAGCCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTAAAAGACCGTAT
TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA
ACACGAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC
TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA
AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGCACAGGCGGTGGCACGCAACAAA
CGGATATGGCTATCGCAGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCACAAAATGCTGGAAAA
ACGATTAAACAAATTCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA
TGAAATCATGGAAAACAACGAACTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes MGAS315	100	100	1
clpP	Streptococcus pyogenes JRS4	100	100	1
clpP	Streptococcus mutans UA159	90.816	100	0.908
clpP	Streptococcus pneumoniae Rx1	90.769	99.49	0.903
clpP	Streptococcus pneumoniae D39	90.769	99.49	0.903
clpP	Streptococcus pneumoniae R6	90.769	99.49	0.903
clpP	Streptococcus pneumoniae TIGR4	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.224	100	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	85.714	100	0.857
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561