Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   D7D53_RS03890 Genome accession   NZ_CP032621
Coordinates   786749..787456 (+) Length   235 a.a.
NCBI ID   WP_033681745.1    Uniprot ID   A0A387B025
Organism   Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 781749..792456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D53_RS03855 (D7D53_03855) - 781944..782615 (+) 672 WP_070527712.1 GTP pyrophosphokinase -
  D7D53_RS03860 (D7D53_03860) - 782599..783417 (+) 819 WP_033681742.1 NAD kinase -
  D7D53_RS03865 (D7D53_03865) - 783414..784310 (+) 897 WP_120770192.1 RluA family pseudouridine synthase -
  D7D53_RS03870 (D7D53_03870) pta 784354..785328 (+) 975 WP_000451571.1 phosphate acetyltransferase -
  D7D53_RS03885 (D7D53_03885) mutY 785518..786693 (+) 1176 WP_120770193.1 A/G-specific adenine glycosylase -
  D7D53_RS03890 (D7D53_03890) micA 786749..787456 (+) 708 WP_033681745.1 response regulator YycF Regulator
  D7D53_RS03895 (D7D53_03895) micB 787449..788798 (+) 1350 WP_120770194.1 cell wall metabolism sensor histidine kinase VicK Regulator
  D7D53_RS03900 (D7D53_03900) vicX 788800..789609 (+) 810 WP_120770195.1 MBL fold metallo-hydrolase Regulator
  D7D53_RS03905 (D7D53_03905) - 789641..789988 (-) 348 WP_120770196.1 PedC/BrcD family bacteriocin maturation disulfide isomerase -
  D7D53_RS03910 (D7D53_03910) - 790100..791818 (-) 1719 WP_120770197.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27079.85 Da        Isoelectric Point: 4.6177

>NTDB_id=317187 D7D53_RS03890 WP_033681745.1 786749..787456(+) (micA) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLASVDNQESDEKKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=317187 D7D53_RS03890 WP_033681745.1 786749..787456(+) (micA) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCGGACATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
GGTTGTAACTGCTTTTAACGGTCGTGAAGCGCTAGAACAATTTGAAGCAGAGCAGCCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGGTTAGAAGTTGCTAAGACTATTCGCAAGACGAGTAGTGTGCCTATTATCATGCTGTCGGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGTTTAGAGCTTGGAGCGGATGACTATGTGACAAAACCCTTCTCAAATCGTGA
GTTGCAGGCACGTGTTAAAGCTCTTCTTCGTCGCACGGACTTGGCTTCTGTAGATAATCAAGAGTCAGATGAAAAGAAAA
CCCAACCCTTGCAAATTGGGGACTTGGAGATTGTGCCAGATGCTTATGTAGCTAAGAAATACGGTGAAGAACTAGATTTA
ACCCACCGTGAATTTGAACTCTTATACCATTTAGCTTCTCATATTGGTCAAGTGATTACACGTGAACATTTGCTTGAAAC
GGTCTGGGGTTATGATTATTTCGGAGATGTTCGGACTGTTGACGTAACTATCAGACGTTTGCGTGAGAAGATTGAAGATA
CACCTAGTCGTCCAGAGTATATCCTAACACGTCGTGGTGTTGGTTATTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A387B025

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

94.017

99.574

0.936
  vicR Streptococcus mutans UA159

77.447

100

0.774
  covR Streptococcus salivarius strain HSISS4

44.589

98.298

0.438
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.723

98.298

0.43
  scnR Streptococcus mutans UA159

38.034

99.574

0.379

Multiple sequence alignment