Detailed information NTG0317142

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: D7D50_RS05850
• Genome accession: NZ_CP032620
• Coordinates: 1155883..1156473 (+)
• Length: 196 a.a.
• NCBI ID: WP_023024046.1
• Uniprot ID: A0A428I0E7
• Organism: Streptococcus koreensis strain KCOM 2890 (=JS71)
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1150883..1161473

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D7D50_RS05840 (D7D50_05840)	mgtA	1152330..1154990 (+)	2661	WP_120701717.1	magnesium-translocating P-type ATPase	-
D7D50_RS05845 (D7D50_05845)	upp	1155091..1155720 (+)	630	WP_023024048.1	uracil phosphoribosyltransferase	-
D7D50_RS05850 (D7D50_05850)	clpP	1155883..1156473 (+)	591	WP_023024046.1	ATP-dependent Clp protease proteolytic subunit	Regulator
D7D50_RS05860 (D7D50_05860)	-	1156749..1157033 (+)	285	WP_023024043.1	DUF2129 domain-containing protein	-
D7D50_RS05865 (D7D50_05865)	-	1157127..1158284 (+)	1158	WP_023024042.1	ABC transporter substrate-binding protein	-
D7D50_RS05870 (D7D50_05870)	-	1158366..1159235 (+)	870	WP_009731472.1	branched-chain amino acid ABC transporter permease	-
D7D50_RS05875 (D7D50_05875)	-	1159239..1160186 (+)	948	WP_023024038.1	branched-chain amino acid ABC transporter permease	-
D7D50_RS05880 (D7D50_05880)	-	1160186..1160950 (+)	765	WP_120701718.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21461.61 Da
• Isoelectric Point: 5.0054

>NTDB_id=317142 D7D50_RS05850 WP_023024046.1 1155883..1156473(+) (clpP) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMVTGPVEDQMANSIIAQLLFLDAQDNTKDIYMYINTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAENSGQ
TIKKIHADAERDNWMTAEETLAYGFIDEIMANNNLG

Nucleotide

• Length: 591 bp

>NTDB_id=317142 D7D50_RS05850 WP_023024046.1 1155883..1156473(+) (clpP) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGATTCCAGTAGTTATTGAACAAACCAGTCGTGGCGAACGCTCGTACGACATCTATTCCCGCTTATTAAAAGACCGTAT
TATCATGGTAACAGGACCGGTAGAAGACCAAATGGCCAATTCGATTATTGCCCAATTGCTCTTCTTGGATGCCCAAGATA
ATACCAAAGATATCTATATGTATATCAATACGCCAGGAGGCTCTGTCTCTGCAGGGTTGGCTATCGTCGATACCATGAAC
TTTATCAAATCAGACGTCCAAACTATTGTTATGGGGATGGCTGCTTCAATGGGAACTGTGATTGCATCAAGTGGTGCCAA
AGGCAAACGTTTCATGTTGCCAAATGCTGAGTACATGATCCACCAACCAATGGGTGGTACTGGTGGCGGTACCCAACAAA
CAGATATGGCGATTGCTGCAGAACACTTGTTGAAAACACGTCACAGATTGGAAAAAATCTTGGCAGAAAATTCAGGTCAA
ACCATCAAGAAAATCCACGCTGATGCAGAACGGGATAATTGGATGACTGCAGAAGAAACCTTAGCTTATGGTTTCATCGA
TGAAATCATGGCCAACAACAATCTTGGATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A428I0E7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes JRS4	91.795	99.49	0.913
clpP	Streptococcus pyogenes MGAS315	91.795	99.49	0.913
clpP	Streptococcus pneumoniae Rx1	91.282	99.49	0.908
clpP	Streptococcus pneumoniae D39	91.282	99.49	0.908
clpP	Streptococcus pneumoniae R6	91.282	99.49	0.908
clpP	Streptococcus pneumoniae TIGR4	91.282	99.49	0.908
clpP	Streptococcus thermophilus LMG 18311	89.744	99.49	0.893
clpP	Streptococcus thermophilus LMD-9	89.744	99.49	0.893
clpP	Streptococcus mutans UA159	88.718	99.49	0.883
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	84.103	99.49	0.837
clpP	Lactococcus lactis subsp. cremoris KW2	83.59	99.49	0.832
clpP	Bacillus subtilis subsp. subtilis str. 168	57.812	97.959	0.566
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561