Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   D6022_RS00250 Genome accession   NZ_CP032538
Coordinates   23811..24407 (+) Length   198 a.a.
NCBI ID   WP_003185550.1    Uniprot ID   A0A1J6GJE1
Organism   Bacillus licheniformis strain MT-B06     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 153..24407 23811..24407 within 0


Gene organization within MGE regions


Location: 153..24407
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D6022_RS00010 - 153..536 (-) 384 WP_020450356.1 HK97-gp10 family putative phage morphogenesis protein -
  D6022_RS00015 - 536..862 (-) 327 WP_017474687.1 phage head closure protein -
  D6022_RS00020 - 852..1145 (-) 294 WP_017474688.1 head-tail connector protein -
  D6022_RS00025 - 1203..1637 (-) 435 WP_020450355.1 collagen-like protein -
  D6022_RS00030 - 1661..2863 (-) 1203 WP_120155418.1 phage major capsid protein -
  D6022_RS00035 - 2912..3508 (-) 597 WP_073412029.1 HK97 family phage prohead protease -
  D6022_RS00040 - 3501..4742 (-) 1242 WP_073412030.1 phage portal protein -
  D6022_RS00045 - 4747..4950 (-) 204 WP_017474257.1 hypothetical protein -
  D6022_RS00050 - 4971..6677 (-) 1707 WP_120155421.1 terminase large subunit -
  D6022_RS00055 - 6670..7164 (-) 495 WP_017474594.1 phage terminase small subunit P27 family -
  D6022_RS00060 - 7398..7661 (-) 264 WP_017474631.1 Gp49 family protein -
  D6022_RS00070 - 8041..8298 (-) 258 WP_017474629.1 hypothetical protein -
  D6022_RS00075 - 8301..9008 (-) 708 WP_120155426.1 hypothetical protein -
  D6022_RS00080 - 8996..9241 (-) 246 WP_120155430.1 hypothetical protein -
  D6022_RS00085 - 9244..9465 (-) 222 WP_048407332.1 hypothetical protein -
  D6022_RS24710 - 9820..10164 (-) 345 WP_120155437.1 type II toxin-antitoxin system PemK/MazF family toxin -
  D6022_RS00095 - 10166..10369 (-) 204 WP_017474601.1 hypothetical protein -
  D6022_RS00100 - 10706..11248 (-) 543 WP_017474600.1 site-specific integrase -
  D6022_RS00105 - 11248..11688 (-) 441 WP_017474599.1 ArpU family phage packaging/lysis transcriptional regulator -
  D6022_RS24440 - 11703..11831 (-) 129 WP_017474598.1 hypothetical protein -
  D6022_RS00110 - 11986..12234 (-) 249 WP_017474597.1 hypothetical protein -
  D6022_RS00115 - 12234..12413 (-) 180 WP_120155440.1 hypothetical protein -
  D6022_RS00120 - 12410..12601 (-) 192 WP_026080838.1 hypothetical protein -
  D6022_RS00125 - 12598..12996 (-) 399 WP_120155445.1 YopX family protein -
  D6022_RS00130 - 12993..13460 (-) 468 WP_120155450.1 YopX family protein -
  D6022_RS00145 - 13971..14204 (-) 234 WP_017474645.1 hypothetical protein -
  D6022_RS00150 - 14240..14440 (-) 201 WP_017474644.1 XtrA/YqaO family protein -
  D6022_RS00155 - 14512..14661 (-) 150 WP_017475012.1 BH0509 family protein -
  D6022_RS00160 - 14766..15323 (-) 558 WP_225852969.1 hypothetical protein -
  D6022_RS24715 - 15311..15469 (-) 159 WP_017475014.1 DUF6906 family protein -
  D6022_RS23755 - 15466..15624 (-) 159 WP_017475015.1 hypothetical protein -
  D6022_RS00165 - 15638..16471 (-) 834 WP_120155736.1 ATP-binding protein -
  D6022_RS00170 - 16455..17312 (-) 858 WP_120155455.1 conserved phage C-terminal domain-containing protein -
  D6022_RS00175 - 17305..17535 (-) 231 WP_026080815.1 hypothetical protein -
  D6022_RS00180 - 17589..17855 (+) 267 WP_017474557.1 hypothetical protein -
  D6022_RS00185 - 17852..18088 (-) 237 WP_073461319.1 hypothetical protein -
  D6022_RS00190 - 18090..18335 (-) 246 WP_017474860.1 hypothetical protein -
  D6022_RS23760 - 18382..18543 (-) 162 WP_161517572.1 hypothetical protein -
  D6022_RS00195 - 18598..18810 (+) 213 WP_009330098.1 hypothetical protein -
  D6022_RS00200 - 18807..19010 (-) 204 WP_017475041.1 hypothetical protein -
  D6022_RS00205 - 19118..19516 (-) 399 WP_120155459.1 hypothetical protein -
  D6022_RS00210 - 19529..20233 (-) 705 WP_120155462.1 Rha family transcriptional regulator -
  D6022_RS00215 - 20252..20572 (-) 321 WP_017473907.1 DUF771 domain-containing protein -
  D6022_RS00220 - 20584..20826 (-) 243 WP_017473906.1 helix-turn-helix transcriptional regulator -
  D6022_RS00225 - 21002..21334 (+) 333 WP_017473905.1 helix-turn-helix domain-containing protein -
  D6022_RS00230 - 21338..21790 (+) 453 WP_017473904.1 ImmA/IrrE family metallo-endopeptidase -
  D6022_RS00235 - 21807..22919 (+) 1113 WP_017473903.1 tyrosine-type recombinase/integrase -
  D6022_RS00245 - 23253..23570 (-) 318 WP_009329632.1 TM2 domain-containing protein -
  D6022_RS00250 clpP 23811..24407 (+) 597 WP_003185550.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21803.99 Da        Isoelectric Point: 4.7982

>NTDB_id=316803 D6022_RS00250 WP_003185550.1 23811..24407(+) (clpP) [Bacillus licheniformis strain MT-B06]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPQVSTICTGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILSLRDKLNKILAERTGQ
PLEVIERDTDRDNFKTAEEAKEYGLIDKVLTRNIDAQK

Nucleotide


Download         Length: 597 bp        

>NTDB_id=316803 D6022_RS00250 WP_003185550.1 23811..24407(+) (clpP) [Bacillus licheniformis strain MT-B06]
ATGAATTTAATACCTACAGTCATTGAACAGACGAACCGCGGGGAAAGAGCGTATGACATTTACTCACGCTTGTTGAAAGA
CCGTATCATTATGCTGGGATCAGCAATCGATGACAATGTTGCGAACTCCATCGTATCTCAGCTTCTATTCCTTGAAGCCG
AAGATCCAGAAAAAGATATCAGCATCTATATCAACAGCCCTGGCGGCTCCATCACAGCCGGTATGGCGATTTATGACACC
ATGCAGTTTATTAAACCGCAAGTCTCCACGATTTGTACGGGAATGGCGGCATCCATGGGTGCGTTCCTTCTTGCAGCCGG
CGAGAAAGGGAAGCGCTACGCTCTTCCAAACAGTGAAGTCATGATCCACCAGCCGCTTGGCGGAGCGCAGGGTCAGGCGA
CTGAAATTGAAATTGCCGCGAAACGCATTCTTTCATTGCGCGACAAGCTGAACAAAATCCTTGCAGAGCGCACTGGGCAG
CCGCTTGAAGTAATCGAGCGCGATACAGACCGCGACAACTTCAAAACGGCTGAAGAAGCAAAAGAATACGGCCTGATTGA
TAAAGTGCTTACACGCAATATCGACGCACAGAAGTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1J6GJE1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

92.386

99.495

0.919
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.229

96.97

0.662
  clpP Streptococcus thermophilus LMG 18311

58.031

97.475

0.566
  clpP Streptococcus thermophilus LMD-9

58.031

97.475

0.566
  clpP Lactococcus lactis subsp. cremoris KW2

56.995

97.475

0.556
  clpP Streptococcus pneumoniae Rx1

56.995

97.475

0.556
  clpP Streptococcus pneumoniae D39

56.995

97.475

0.556
  clpP Streptococcus pneumoniae R6

56.995

97.475

0.556
  clpP Streptococcus pneumoniae TIGR4

56.995

97.475

0.556
  clpP Streptococcus pyogenes JRS4

55.44

97.475

0.54
  clpP Streptococcus pyogenes MGAS315

55.44

97.475

0.54
  clpP Streptococcus mutans UA159

54.639

97.98

0.535
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

54.922

97.475

0.535

Multiple sequence alignment