Detailed information NTG0315816

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: LLW34_RS06250
• Genome accession: NZ_CP032430
• Coordinates: 1188327..1189175 (-)
• Length: 282 a.a.
• NCBI ID: WP_011676300.1
• Uniprot ID: A0A896TAG0
• Organism: Lactococcus cremoris strain W34
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1183327..1194175

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLW34_RS06235 (LLW34_1205)	xerS	1183397..1184467 (+)	1071	WP_014572599.1	tyrosine recombinase XerS	-
LLW34_RS06240 (LLW34_1206)	trmFO	1184517..1185863 (-)	1347	WP_014572600.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
LLW34_RS06245 (LLW34_1207)	topA	1185935..1188061 (-)	2127	WP_014572601.1	type I DNA topoisomerase	-
LLW34_RS06250 (LLW34_1208)	dprA	1188327..1189175 (-)	849	WP_011676300.1	DNA-processing protein DprA	Machinery gene
LLW34_RS06255 (LLW34_1209)	-	1189324..1189704 (-)	381	WP_014572603.1	RidA family protein	-
LLW34_RS06260 (LLW34_1210)	budA	1189744..1190454 (-)	711	WP_011676302.1	acetolactate decarboxylase	-
LLW34_RS06265 (LLW34_1211)	ilvA	1190589..1191839 (-)	1251	WP_014572605.1	threonine ammonia-lyase IlvA	-
LLW34_RS06270 (LLW34_1212)	ilvC	1191898..1192920 (-)	1023	WP_205288465.1	ketol-acid reductoisomerase	-
LLW34_RS06275 (LLW34_1213)	ilvN	1192966..1193442 (-)	477	WP_021037263.1	acetolactate synthase small subunit	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31955.09 Da
• Isoelectric Point: 9.8385

>NTDB_id=315816 LLW34_RS06250 WP_011676300.1 1188327..1189175(-) (dprA) [Lactococcus cremoris strain W34]
MITNFDLFRWKKAGMTNLGVNKLLKFFRKYDIKISLRQMGQVAQVKSIPNFIEQYKNQDVKKLRIDYKKFSSFSILDDLY
PERLREIYNPPVLIFYQGNIDLLKNPKLAFVGSRLAGQSGIKAVQKIITELNQSFTIVSGLAKGIDTASHLSAIKTKTPT
IAVIGTGLDIFYPLENRKIQEYLAKNQLVLSEYSLGEKPLKYHFPERNRIIAGLSRGVVVVEEKLRSGSLITCERALEEG
RDIFAIPGNIADGTSDGCNHLIQQGAKLVYQAQDILEEYLYN

Nucleotide

• Length: 849 bp

>NTDB_id=315816 LLW34_RS06250 WP_011676300.1 1188327..1189175(-) (dprA) [Lactococcus cremoris strain W34]
ATGATTACAAATTTTGATTTATTTCGTTGGAAAAAAGCAGGAATGACCAATCTTGGTGTAAATAAGCTCTTAAAATTTTT
CCGCAAATATGATATAAAAATAAGCTTACGACAAATGGGACAAGTGGCTCAAGTCAAATCAATCCCTAACTTTATCGAAC
AATATAAAAATCAGGACGTAAAGAAACTCAGGATAGACTATAAAAAATTTTCCTCCTTTTCCATTCTTGATGACCTTTAT
CCCGAGCGTCTAAGAGAAATCTACAACCCACCCGTTTTAATTTTTTATCAGGGAAATATTGATTTATTAAAAAATCCTAA
ACTTGCCTTTGTTGGAAGCCGCCTAGCAGGTCAATCAGGGATAAAAGCTGTCCAAAAAATTATCACAGAATTGAATCAAT
CCTTTACAATAGTAAGCGGGCTTGCTAAAGGGATTGACACAGCCAGCCATCTGTCAGCAATTAAAACTAAAACACCAACA
ATTGCTGTTATTGGTACAGGATTGGATATTTTCTATCCACTAGAAAATCGTAAAATACAGGAATATCTAGCAAAAAATCA
ATTAGTTTTAAGTGAATATTCATTAGGCGAAAAACCACTTAAATACCACTTTCCAGAGCGCAATCGAATTATTGCTGGTC
TTTCACGGGGAGTTGTTGTCGTGGAAGAAAAATTAAGAAGTGGCAGTTTAATCACCTGTGAAAGGGCACTGGAAGAAGGA
AGAGATATCTTTGCCATCCCTGGAAATATTGCAGATGGAACATCTGATGGCTGTAATCATCTTATTCAACAAGGAGCAAA
ACTTGTCTATCAAGCTCAAGATATTTTAGAAGAATATTTGTACAATTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (69-270)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (2-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Lactococcus lactis subsp. cremoris KW2	97.872	100	0.979
dprA	Streptococcus mutans UA159	58.993	98.582	0.582
dprA/cilB/dalA	Streptococcus mitis SK321	55.714	99.291	0.553
dprA/cilB/dalA	Streptococcus pneumoniae R6	55.357	99.291	0.55
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	55.357	99.291	0.55
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	55.357	99.291	0.55
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	55.357	99.291	0.55
dprA/cilB/dalA	Streptococcus pneumoniae D39	55.357	99.291	0.55
dprA	Bacillus subtilis subsp. subtilis str. 168	39.273	97.518	0.383
dprA	Vibrio campbellii strain DS40M4	35.314	100	0.379
dprA	Legionella pneumophila strain ERS1305867	38.768	97.872	0.379
dprA	Haemophilus influenzae Rd KW20	39.259	95.745	0.376