Detailed information NTG0315198

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: D4A37_RS13890
• Genome accession: NZ_CP032365
• Coordinates: 2735882..2736463 (-)
• Length: 193 a.a.
• NCBI ID: WP_000991621.1
• Uniprot ID: A0A4R4BLF5
• Organism: Bacillus wiedmannii strain SR52
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2730882..2741463

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D4A37_RS13860	-	2731165..2731989 (-)	825	WP_074650819.1	PP2C family serine/threonine-protein phosphatase	-
D4A37_RS13865	-	2732102..2732269 (-)	168	WP_000508408.1	hypothetical protein	-
D4A37_RS13870	-	2732487..2732722 (+)	236	Protein_2645	hypothetical protein	-
D4A37_RS13875	-	2732772..2733608 (-)	837	WP_001084768.1	proline/glycine betaine ABC transporter permease	-
D4A37_RS13880	-	2733601..2734806 (-)	1206	WP_000370613.1	glycine betaine/L-proline ABC transporter ATP-binding protein	-
D4A37_RS13885	-	2734978..2735835 (+)	858	WP_000727302.1	glycine betaine ABC transporter substrate-binding protein	-
D4A37_RS13890	clpP	2735882..2736463 (-)	582	WP_000991621.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
D4A37_RS13895	-	2736485..2737171 (-)	687	WP_000337525.1	RNA polymerase subunit sigma-70	-
D4A37_RS13900	-	2737315..2737635 (+)	321	WP_001125375.1	2Fe-2S iron-sulfur cluster-binding protein	-
D4A37_RS13905	rpiA	2737637..2738305 (+)	669	WP_000931539.1	ribose 5-phosphate isomerase A	-
D4A37_RS13910	-	2738412..2738846 (+)	435	WP_000555786.1	GNAT family N-acetyltransferase	-
D4A37_RS13915	-	2738977..2740344 (-)	1368	WP_048566256.1	lytic polysaccharide monooxygenase	-

Sequence

Protein

• Length: 193 a.a.
• Molecular weight: 21275.49 Da
• Isoelectric Point: 4.9215

>NTDB_id=315198 D4A37_RS13890 WP_000991621.1 2735882..2736463(-) (clpP) [Bacillus wiedmannii strain SR52]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIIIIGSEINDQVASSVVAQLLFLEAEDAEKDIYLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAQGQATEIEITAKRILKLKRDINKMIAEKTGQ
SIERVAHDTERDYFMTAEEAKEYGIVDDVVTKK

Nucleotide

• Length: 582 bp

>NTDB_id=315198 D4A37_RS13890 WP_000991621.1 2735882..2736463(-) (clpP) [Bacillus wiedmannii strain SR52]
ATGAATGCAATTCCATATGTAGTAGAACAAACGAAATTAGGAGAACGTTCCTATGATATATATTCAAGGTTATTAAAAGA
TCGCATTATTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTTGTAGCTCAATTATTATTTTTAGAAGCGG
AAGATGCAGAGAAAGATATTTATTTATACATCAATAGCCCAGGTGGTTCAACAACAGCGGGTTTTGCCATATTAGATACG
ATGAATCTCATTAAACCAGATGTACAAACGCTATGCATGGGATTTGCAGCATCATTTGGTGCATTGTTATTATTATCAGG
TGCAAAAGGAAAACGGTTTGCGCTCCCTAACAGTGAAATTATGATTCATCAGCCACTTGGTGGTGCGCAAGGCCAGGCAA
CAGAAATTGAAATAACAGCGAAAAGAATACTAAAGTTAAAGCGTGATATTAATAAAATGATTGCAGAAAAAACAGGGCAA
TCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACTGCTGAAGAAGCGAAAGAATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (14-192)

3D structure

• AlphaFold DB: A0A4R4BLF5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	68.586	98.964	0.679
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.254	97.927	0.668
clpP	Streptococcus pneumoniae Rx1	56.771	99.482	0.565
clpP	Streptococcus pneumoniae D39	56.771	99.482	0.565
clpP	Streptococcus pneumoniae R6	56.771	99.482	0.565
clpP	Streptococcus pneumoniae TIGR4	56.771	99.482	0.565
clpP	Streptococcus thermophilus LMG 18311	55.729	99.482	0.554
clpP	Streptococcus thermophilus LMD-9	55.729	99.482	0.554
clpP	Streptococcus pyogenes JRS4	55.556	97.927	0.544
clpP	Streptococcus pyogenes MGAS315	55.556	97.927	0.544
clpP	Streptococcus mutans UA159	54.497	97.927	0.534
clpP	Lactococcus lactis subsp. cremoris KW2	53.968	97.927	0.528
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	51.852	97.927	0.508