Detailed information    

insolico Bioinformatically predicted

Overview


Name   clpP   Type   Regulator
Locus tag   LL1196_RS03845 Genome accession   NZ_CP032148
Coordinates   727525..728124 (-) Length   199 a.a.
NCBI ID   WP_011834647.1    Uniprot ID   A0A166TF89
Organism   Lactococcus cremoris strain 1196     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 727510..741959 727525..728124 within 0


Gene organization within MGE regions


Location: 727510..741959
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL1196_RS03845 (LL1196_0720) clpP 727525..728124 (-) 600 WP_011834647.1 ATP-dependent Clp protease proteolytic subunit Regulator
  LL1196_RS03850 (LL1196_0721) - 728320..728850 (+) 531 WP_011675638.1 hypothetical protein -
  LL1196_RS03855 (LL1196_0722) spx 729020..729418 (+) 399 WP_003129597.1 transcriptional regulator Spx -
  LL1196_RS03860 (LL1196_03010) - 729569..729703 (-) 135 WP_014572996.1 hypothetical protein -
  LL1196_RS03865 (LL1196_0723) - 729800..730963 (-) 1164 WP_021216083.1 ABC transporter permease -
  LL1196_RS03870 (LL1196_03015) - 731291..733971 (+) 2681 Protein_734 cation-translocating P-type ATPase -
  LL1196_RS03875 (LL1196_0727) - 734030..735141 (+) 1112 WP_262668432.1 IS3-like element IS981 family transposase -
  LL1196_RS03880 (LL1196_03020) - 735309..735455 (+) 147 WP_011675641.1 hypothetical protein -
  LL1196_RS03885 (LL1196_0728) - 735562..736452 (+) 891 WP_205536422.1 IS982 family transposase -
  LL1196_RS03890 (LL1196_0729) istB 736773..737531 (-) 759 WP_003331414.1 IS21-like element IS712 family helper ATPase IstB -
  LL1196_RS03895 (LL1196_0730) istA 737543..738766 (-) 1224 WP_003331415.1 IS21-like element IS712 family transposase -
  LL1196_RS03900 (LL1196_0732) - 738964..739782 (+) 819 WP_031288961.1 polysaccharide deacetylase family protein -
  LL1196_RS03905 (LL1196_0734) - 739952..741099 (+) 1148 WP_134794176.1 IS3 family transposase -

Sequence


Protein


Download         Length: 199 a.a.        Molecular weight: 22052.21 Da        Isoelectric Point: 4.7423

>NTDB_id=314077 LL1196_RS03845 WP_011834647.1 727525..728124(-) (clpP) [Lactococcus cremoris strain 1196]
MGYLVPTVIEQSSRGERAYDIYSRLLKDRIIMLTGPVEDGMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVD
TMNFIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYLIHQPMGGAGQGTQQTDMAIVAEQLLKTRKRLEQILADN
SNRSLEQIHKDAERDHWMDAKETLEYGFIDEIMENNSLK

Nucleotide


Download         Length: 600 bp        

>NTDB_id=314077 LL1196_RS03845 WP_011834647.1 727525..728124(-) (clpP) [Lactococcus cremoris strain 1196]
ATGGGTTATTTAGTACCTACCGTTATTGAACAATCAAGCCGTGGTGAACGTGCTTATGATATTTATTCACGACTTTTAAA
AGACCGTATTATCATGCTGACAGGACCTGTTGAAGATGGTATGGCAAATTCTATCATTGCCCAACTTCTTTTCTTGGATG
CACAAGATAATACTAAAGACATTTATCTCTATGTAAACACCCCTGGTGGTTCTGTATCAGCTGGGCTCGCTATCGTGGAT
ACAATGAACTTTATCAAATCGGATGTCCAAACTATCGTTATGGGAATGGCTGCTTCTATGGGAACAATCATCGCCTCAAG
CGGTACTAAGGGTAAACGATTCATGTTACCAAATGCTGAATACCTCATTCACCAACCAATGGGTGGTGCAGGTCAAGGTA
CTCAACAAACTGATATGGCAATCGTCGCCGAACAACTTTTGAAAACACGTAAACGTTTGGAACAAATCCTTGCTGATAAT
TCTAATCGCTCACTTGAACAAATTCACAAAGATGCTGAACGTGACCATTGGATGGATGCCAAAGAAACTTTAGAATATGG
TTTCATTGATGAAATTATGGAAAATAATTCATTAAAATAA

Domains


Predicted by InterproScan.

(14-195)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A166TF89

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Lactococcus lactis subsp. cremoris KW2

100

100

1

  clpP Lactococcus lactis subsp. lactis strain DGCC12653

99.497

100

0.995

  clpP Streptococcus mutans UA159

87.245

98.492

0.859

  clpP Streptococcus thermophilus LMD-9

86.735

98.492

0.854

  clpP Streptococcus thermophilus LMG 18311

86.735

98.492

0.854

  clpP Streptococcus pyogenes MGAS315

85.714

98.492

0.844

  clpP Streptococcus pyogenes JRS4

85.714

98.492

0.844

  clpP Streptococcus pneumoniae D39

84.615

97.99

0.829

  clpP Streptococcus pneumoniae TIGR4

84.615

97.99

0.829

  clpP Streptococcus pneumoniae R6

84.615

97.99

0.829

  clpP Streptococcus pneumoniae Rx1

84.615

97.99

0.829

  clpP Bacillus subtilis subsp. subtilis str. 168

57.895

95.477

0.553

  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.995

96.985

0.553


Multiple sequence alignment