Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   SEZ_RS06770 Genome accession   NC_011134
Coordinates   1434932..1435642 (-) Length   236 a.a.
NCBI ID   WP_012515994.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus MGCS10565     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1429932..1440642
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SEZ_RS10125 (Sez_1392) - 1430380..1431150 (-) 771 WP_322006259.1 hypothetical protein -
  SEZ_RS10130 (Sez_1393) - 1431196..1431891 (-) 696 WP_338141007.1 helix-turn-helix domain-containing protein -
  SEZ_RS06760 (Sez_1394) vicX 1432774..1433583 (-) 810 WP_012515992.1 MBL fold metallo-hydrolase Regulator
  SEZ_RS06765 (Sez_1395) vicK 1433587..1434939 (-) 1353 WP_012515993.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SEZ_RS06770 (Sez_1396) vicR 1434932..1435642 (-) 711 WP_012515994.1 response regulator YycF Regulator
  SEZ_RS06775 (Sez_1397) - 1435839..1436858 (-) 1020 WP_012515995.1 DUF3114 domain-containing protein -
  SEZ_RS06780 (Sez_1398) - 1436904..1438166 (-) 1263 WP_012515996.1 AMP-binding protein -
  SEZ_RS06785 (Sez_1399) - 1438156..1439271 (-) 1116 WP_012515997.1 acetyl-CoA C-acyltransferase -
  SEZ_RS06790 (Sez_1400) - 1439268..1439807 (-) 540 WP_012515998.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26981.84 Da        Isoelectric Point: 4.9038

>NTDB_id=31381 SEZ_RS06770 WP_012515994.1 1434932..1435642(-) (vicR) [Streptococcus equi subsp. zooepidemicus MGCS10565]
MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKAYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=31381 SEZ_RS06770 WP_012515994.1 1434932..1435642(-) (vicR) [Streptococcus equi subsp. zooepidemicus MGCS10565]
ATGAAGAAAATACTGATTGTTGATGATGAAAAGCCGATTTCTGATATCATTAAATTTAATCTGACAAAGGAAGGCTATGA
TACGGTCACAGCCTTTGATGGCAAAGAGGCCGTTGCAGTCTTTGAAGAGGAAAAGCCAGATTTGATTATTTTGGATTTGA
TGCTTCCTGAGCTAGATGGTCTTGAGGTAGCCAAGGAAATCCGCAAGACCAGCCATATTCCTATCATCATGCTATCTGCT
AAGGATAGCGAATTTGATAAGGTGATTGGCCTTGAAATAGGGGCCGATGATTATGTGACTAAGCCCTTTTCAAATCGTGA
GCTGCTGGCGCGTGTCAAGGCACATTTGCGTCGGACAGAGACTATTGAGACAGCAGTAGCCGAAGAAAATGCCTCCTCAG
GCTCTCAGGAGCTGACCATCGGCAATCTACAGATTTTGCCAGATGCCTTTATTGCTAAAAAGCATGGTCAAGAGGTTGAG
CTGACCCATCGTGAGTTTGAATTGCTGCATCATCTGGCAAACCATATCGGACAGGTCATGACACGTGAGCATTTGCTTGA
GACCGTATGGGGCTACGATTATTTTGGCGATGTCCGAACCGTTGACGTTACTATCCGTCGCCTGCGCGAAAAAATAGAGG
ATACACCGAGTCGTCCAGAGTATATTTTGACAAGACGTGGTGTTGGGTACTACATGAAGGCTTATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

88.983

100

0.89
  micA Streptococcus pneumoniae Cp1015

78.112

98.729

0.771
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

38.034

99.153

0.377

Multiple sequence alignment