Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   SEZ_RS06765 Genome accession   NC_011134
Coordinates   1433587..1434939 (-) Length   450 a.a.
NCBI ID   WP_012515993.1    Uniprot ID   B4U414
Organism   Streptococcus equi subsp. zooepidemicus MGCS10565     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1428587..1439939
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SEZ_RS06745 (Sez_1391) rnc 1429429..1430121 (-) 693 WP_037581642.1 ribonuclease III -
  SEZ_RS10125 (Sez_1392) - 1430380..1431150 (-) 771 WP_322006259.1 hypothetical protein -
  SEZ_RS10130 (Sez_1393) - 1431196..1431891 (-) 696 WP_338141007.1 helix-turn-helix domain-containing protein -
  SEZ_RS06760 (Sez_1394) vicX 1432774..1433583 (-) 810 WP_012515992.1 MBL fold metallo-hydrolase Regulator
  SEZ_RS06765 (Sez_1395) vicK 1433587..1434939 (-) 1353 WP_012515993.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SEZ_RS06770 (Sez_1396) vicR 1434932..1435642 (-) 711 WP_012515994.1 response regulator YycF Regulator
  SEZ_RS06775 (Sez_1397) - 1435839..1436858 (-) 1020 WP_012515995.1 DUF3114 domain-containing protein -
  SEZ_RS06780 (Sez_1398) - 1436904..1438166 (-) 1263 WP_012515996.1 AMP-binding protein -
  SEZ_RS06785 (Sez_1399) - 1438156..1439271 (-) 1116 WP_012515997.1 acetyl-CoA C-acyltransferase -
  SEZ_RS06790 (Sez_1400) - 1439268..1439807 (-) 540 WP_012515998.1 hypothetical protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51528.90 Da        Isoelectric Point: 5.4026

>NTDB_id=31380 SEZ_RS06765 WP_012515993.1 1433587..1434939(-) (vicK) [Streptococcus equi subsp. zooepidemicus MGCS10565]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDDDKMTQVIENILNNAIKYSPDGGKIVVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=31380 SEZ_RS06765 WP_012515993.1 1433587..1434939(-) (vicK) [Streptococcus equi subsp. zooepidemicus MGCS10565]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCACAAGATAAGAGATTTGATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAATGACCTATCAGAT
GTTTTTCGTCTGACTCATGAAAACCTTGCTCAAGAAAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGCGAGCAGG
CCTTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCCCCTTATACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAACCGTCGTAATGATACAGGAGAATTTGTTTCCCTGCGGCTGCGCTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTGGTTGTTGTACTTCATGACACGACTGAGCAGGAAAAGGAAGAGCGCGAGCGCAGACTCTTTGTTT
CAAATGTTAGCCATGAGCTGCGGACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATCGCTCCAAGCTTTATAAAGGTCTCACTAGATGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
CCTCTCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACAAGCACAGGAAAATCCTATGAAATTGTCAGAGATTACCCCATTACCTCT
ATTTGGCTAGAAATTGACGATGACAAAATGACGCAGGTTATCGAAAATATTTTAAACAATGCGATCAAATATTCACCCGA
TGGCGGAAAAATTGTCGTCAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGCTTGGGTATTC
CAAAAAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGGAGTAGAGCTCAAGGAGGGACCGGG
CTAGGCCTAGCGATTGCTAAAGAAATTATTAAGCAGCACCGAGGCTTTATTTGGGCTAAGAGTGATTATGGCAAGGGCTC
AACCTTTACCATTGTGTTACCTTATGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4U414

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631

Multiple sequence alignment