Detailed information NTG0313535

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: D2E16_RS08260
• Genome accession: NZ_CP032064
• Coordinates: 1720244..1720834 (-)
• Length: 196 a.a.
• NCBI ID: WP_002937303.1
• Uniprot ID: A0A0K2E545
• Organism: Streptococcus suis strain YSJ17
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1715244..1725834

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D2E16_RS08235 (D2E16_08490)	-	1715747..1716511 (-)	765	WP_024376797.1	ABC transporter ATP-binding protein	-
D2E16_RS08240 (D2E16_08495)	-	1716511..1717458 (-)	948	WP_192368985.1	branched-chain amino acid ABC transporter permease	-
D2E16_RS08245 (D2E16_08500)	-	1717461..1718348 (-)	888	WP_192368984.1	branched-chain amino acid ABC transporter permease	-
D2E16_RS08250 (D2E16_08505)	-	1718544..1719713 (-)	1170	WP_044760026.1	ABC transporter substrate-binding protein	-
D2E16_RS08255 (D2E16_08510)	-	1719845..1720117 (-)	273	WP_024381609.1	YlbG family protein	-
D2E16_RS08260 (D2E16_08515)	clpP	1720244..1720834 (-)	591	WP_002937303.1	ATP-dependent Clp protease proteolytic subunit	Regulator
D2E16_RS08265 (D2E16_08520)	upp	1720951..1721580 (-)	630	WP_002937309.1	uracil phosphoribosyltransferase	-
D2E16_RS08270 (D2E16_08525)	-	1721663..1723279 (-)	1617	WP_192368983.1	glycoside hydrolase family 13 protein	-
D2E16_RS08275 (D2E16_08530)	gtfA	1723352..1724800 (-)	1449	WP_192368982.1	sucrose phosphorylase	-
D2E16_RS08280 (D2E16_08535)	-	1724870..1725700 (-)	831	WP_002937312.1	carbohydrate ABC transporter permease	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21494.74 Da
• Isoelectric Point: 5.7110

>NTDB_id=313535 D2E16_RS08260 WP_002937303.1 1720244..1720834(-) (clpP) [Streptococcus suis strain YSJ17]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDPTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGTAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNKLEKILADNSGK
TVKQIHKDAERDYWMSAEETLAYGFIDQIMDNTKVK

Nucleotide

• Length: 591 bp

>NTDB_id=313535 D2E16_RS08260 WP_002937303.1 1720244..1720834(-) (clpP) [Streptococcus suis strain YSJ17]
ATGATTCCAGTAGTTATTGAACAAACTAGCCGTGGTGAGCGTTCTTATGATATTTACTCACGCCTTTTGAAAGACCGTAT
TATCATGTTGACAGGACCAGTTGAGGACAACATGGCAAACTCTATCATTGCACAATTGCTTTTCCTTGATGCCCAAGACC
CAACCAAAGATATTTACCTTTATGTAAATACACCTGGTGGATCTGTGTCAGCTGGTCTAGCTATTGTCGATACCATGAAC
TTTATTAAAGCTGATGTTCAAACCATCGTTATGGGAACAGCTGCGAGCATGGGAACCATCATCGCTTCAAGCGGTGCCAA
GGGCAAACGTTTCATGTTGCCAAATGCGGAATACATGATTCACCAGCCAATGGGTGGAACTGGTGGTGGCACTCAGCAAA
CAGATATGGCCATTGCAGCAGAACACCTATTAAAAACACGTAATAAGCTAGAAAAAATCTTGGCAGACAACTCAGGTAAG
ACAGTCAAGCAAATCCACAAGGATGCGGAACGTGATTACTGGATGTCAGCTGAAGAAACCTTGGCTTACGGATTTATTGA
CCAGATTATGGACAATACAAAAGTCAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A0K2E545

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes JRS4	92.347	100	0.923
clpP	Streptococcus pyogenes MGAS315	92.347	100	0.923
clpP	Streptococcus mutans UA159	90.306	100	0.903
clpP	Streptococcus pneumoniae R6	88.776	100	0.888
clpP	Streptococcus pneumoniae Rx1	88.776	100	0.888
clpP	Streptococcus pneumoniae D39	88.776	100	0.888
clpP	Streptococcus pneumoniae TIGR4	88.776	100	0.888
clpP	Streptococcus thermophilus LMG 18311	88.776	100	0.888
clpP	Streptococcus thermophilus LMD-9	88.776	100	0.888
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	84.184	100	0.842
clpP	Lactococcus lactis subsp. cremoris KW2	83.673	100	0.837
clpP	Bacillus subtilis subsp. subtilis str. 168	58.163	100	0.582
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.549	98.469	0.577