Detailed information NTG0312336

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: D1O36_RS05630
• Genome accession: NZ_CP031881
• Coordinates: 1027228..1027935 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST106
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1022228..1032935

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1O36_RS05605 (D1O36_05635)	yidA	1022579..1023388 (+)	810	WP_011226081.1	sugar-phosphatase	-
D1O36_RS05610 (D1O36_05640)	-	1023390..1024604 (+)	1215	WP_002953123.1	aminoacyltransferase	-
D1O36_RS05615 (D1O36_05645)	-	1024656..1025017 (-)	362	Protein_1036	YbaN family protein	-
D1O36_RS05620 (D1O36_05650)	vicX	1025077..1025886 (-)	810	WP_024704147.1	MBL fold metallo-hydrolase	Regulator
D1O36_RS05625 (D1O36_05655)	vicK	1025895..1027235 (-)	1341	WP_134973270.1	cell wall metabolism sensor histidine kinase VicK	Regulator
D1O36_RS05630 (D1O36_05660)	vicR	1027228..1027935 (-)	708	WP_011681206.1	response regulator YycF	Regulator
D1O36_RS05635 (D1O36_05665)	-	1028462..1029229 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
D1O36_RS05640 (D1O36_05670)	-	1029241..1030074 (+)	834	WP_134973271.1	transporter substrate-binding domain-containing protein	-
D1O36_RS05645 (D1O36_05675)	-	1030092..1030790 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
D1O36_RS05650 (D1O36_05680)	-	1030802..1031452 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
D1O36_RS05655 (D1O36_05685)	endA	1031523..1032404 (-)	882	WP_111679622.1	DNA/RNA non-specific endonuclease	Machinery gene
D1O36_RS05660 (D1O36_05690)	-	1032466..1032654 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=312336 D1O36_RS05630 WP_011681206.1 1027228..1027935(-) (vicR) [Streptococcus thermophilus strain ST106]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=312336 D1O36_RS05630 WP_011681206.1 1027228..1027935(-) (vicR) [Streptococcus thermophilus strain ST106]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387