Detailed information NTG0310851

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: DDV21_RS08800
• Genome accession: NZ_CP031733
• Coordinates: 1837907..1838497 (-)
• Length: 196 a.a.
• NCBI ID: WP_116878025.1
• Uniprot ID: A0A372KM78
• Organism: Streptococcus chenjunshii strain Z15
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1832907..1843497

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DDV21_RS08775 (DDV21_008775)	-	1833655..1834611 (-)	957	WP_116878022.1	branched-chain amino acid ABC transporter permease	-
DDV21_RS08780 (DDV21_008780)	-	1834616..1835485 (-)	870	WP_116878034.1	branched-chain amino acid ABC transporter permease	-
DDV21_RS08785 (DDV21_008785)	-	1835556..1836725 (-)	1170	WP_116878023.1	ABC transporter substrate-binding protein	-
DDV21_RS08790 (DDV21_008790)	-	1836805..1837065 (-)	261	WP_116878024.1	DUF2129 domain-containing protein	-
DDV21_RS08795 (DDV21_008795)	-	1837046..1837543 (-)	498	WP_241964664.1	YlbF family regulator	-
DDV21_RS08800 (DDV21_008800)	clpP	1837907..1838497 (-)	591	WP_116878025.1	ATP-dependent Clp protease proteolytic subunit	Regulator
DDV21_RS08805 (DDV21_008805)	upp	1838586..1839215 (-)	630	WP_116878026.1	uracil phosphoribosyltransferase	-
DDV21_RS08810 (DDV21_008810)	-	1840043..1842490 (-)	2448	WP_241964665.1	glycoside hydrolase family 68 protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21743.87 Da
• Isoelectric Point: 4.4662

>NTDB_id=310851 DDV21_RS08800 WP_116878025.1 1837907..1838497(-) (clpP) [Streptococcus chenjunshii strain Z15]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVTAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGTGSGTQQSDMAIVAEQLLKTRNKLEQILSENSGK
PIEQIHKDAERDYWMDAKETLDYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=310851 DDV21_RS08800 WP_116878025.1 1837907..1838497(-) (clpP) [Streptococcus chenjunshii strain Z15]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGCGGCGAACGTTCTTATGATATCTACTCTCGTCTTTTAAAAGACCGTAT
CATTATGTTAACGGGTCCGGTTGAAGACAATATGGCTAACTCAATCATTGCTCAGTTGCTTTTTCTGGATGCTCAAGACA
ATACCAAGGATATCTACCTTTATGTCAACACTCCTGGCGGTTCTGTCACAGCCGGTCTGGCTATCGTGGATACCATGAAT
TTTATTAAATCCGATGTACAGACCATTGTAATGGGGATGGCAGCTTCCATGGGAACAATTATCGCCTCAAGCGGGGCAAA
AGGCAAGCGGTTTATGCTCCCTAATGCTGAATACCTCATCCACCAGCCAATGGGAGGAACCGGAAGCGGCACACAGCAGT
CAGATATGGCTATTGTTGCGGAGCAGCTCTTAAAAACCCGTAATAAATTAGAACAGATTTTATCAGAAAATTCCGGTAAG
CCGATTGAACAGATTCACAAAGATGCTGAACGCGATTACTGGATGGATGCGAAAGAAACGTTAGACTATGGCTTTATTGA
TGAAATTATGGAAAATAATGAATTGAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A372KM78

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	93.878	100	0.939
clpP	Streptococcus thermophilus LMD-9	89.286	100	0.893
clpP	Streptococcus pyogenes JRS4	89.286	100	0.893
clpP	Streptococcus pyogenes MGAS315	89.286	100	0.893
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	89.286	100	0.893
clpP	Streptococcus thermophilus LMG 18311	89.286	100	0.893
clpP	Lactococcus lactis subsp. cremoris KW2	88.776	100	0.888
clpP	Streptococcus pneumoniae Rx1	87.179	99.49	0.867
clpP	Streptococcus pneumoniae D39	87.179	99.49	0.867
clpP	Streptococcus pneumoniae R6	87.179	99.49	0.867
clpP	Streptococcus pneumoniae TIGR4	87.179	99.49	0.867
clpP	Bacillus subtilis subsp. subtilis str. 168	56.122	100	0.561
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.959	98.469	0.551